LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Imatinib
0.04
uM
LJP6
2
N18
72
hr
1476 3868 3694 1.0471 1.0784
SK-BR-3 Imatinib
0.04
uM
LJP6
3
N18
72
hr
1476 3826 3694 1.0357 1.0595
SK-BR-3 JNK-9L
0.04
uM
LJP6
1
K24
72
hr
1476 2250 3694 0.6091 0.3487
SK-BR-3 JNK-9L
0.04
uM
LJP6
2
K24
72
hr
1476 2651 3694 0.7176 0.5296
SK-BR-3 JNK-9L
0.04
uM
LJP6
3
K24
72
hr
1476 2925 3694 0.7918 0.6532
SK-BR-3 JW-7-24-1
0.04
uM
LJP6
1
B24
72
hr
1476 2669 3694 0.7225 0.5377
SK-BR-3 JW-7-24-1
0.04
uM
LJP6
2
B24
72
hr
1476 2983 3694 0.8075 0.6793
SK-BR-3 JW-7-24-1
0.04
uM
LJP6
3
B24
72
hr
1476 2722 3694 0.7369 0.5616
SK-BR-3 Lapatinib
0.04
uM
LJP6
1
M24
72
hr
1476 1370 3694 0.3709 -0.0481
SK-BR-3 Lapatinib
0.04
uM
LJP6
2
M24
72
hr
1476 1708 3694 0.4624 0.1043
SK-BR-3 Lapatinib
0.04
uM
LJP6
3
M24
72
hr
1476 1514 3694 0.4099 0.0168
SK-BR-3 LDN-193189
0.04
uM
LJP5
1
G06
72
hr
1476 3683 3694 0.9970 0.9950
SK-BR-3 LDN-193189
0.04
uM
LJP5
2
G06
72
hr
1476 3890 3694 1.0530 1.0884
SK-BR-3 LDN-193189
0.04
uM
LJP5
3
G06
72
hr
1476 4259 3694 1.1529 1.2548
SK-BR-3 Linifanib
0.04
uM
LJP6
1
J12
72
hr
1476 3579 3694 0.9689 0.9481
SK-BR-3 Linifanib
0.04
uM
LJP6
2
J12
72
hr
1476 4207 3694 1.1389 1.2313
SK-BR-3 Linifanib
0.04
uM
LJP6
3
J12
72
hr
1476 4324 3694 1.1705 1.2841
SK-BR-3 Linsitinib
0.04
uM
LJP5
1
O24
72
hr
1476 2556 3694 0.6919 0.4868
SK-BR-3 Linsitinib
0.04
uM
LJP5
2
O24
72
hr
1476 2656 3694 0.7190 0.5319
SK-BR-3 Linsitinib
0.04
uM
LJP5
3
O24
72
hr
1476 2584 3694 0.6995 0.4994
SK-BR-3 Mitoxantrone
0.04
uM
LJP5
1
C24
72
hr
1476 1642 3694 0.4445 0.0745
SK-BR-3 Mitoxantrone
0.04
uM
LJP5
2
C24
72
hr
1476 1473 3694 0.3988 -0.0017
SK-BR-3 Mitoxantrone
0.04
uM
LJP5
3
C24
72
hr
1476 1366 3694 0.3698 -0.0499
SK-BR-3 Mitoxantrone
0.04
uM
LJP6
1
C24
72
hr
1476 1333 3694 0.3609 -0.0648
SK-BR-3 Mitoxantrone
0.04
uM
LJP6
2
C24
72
hr
1476 1623 3694 0.4394 0.0660