LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Mitoxantrone
0.04
uM
LJP6
 3
C24
 72
hr
 1476 1516 3694 0.4104 0.0177
SK-BR-3 MK2206
0.04
uM
LJP6
 1
F06
 72
hr
 1476 3469 3694 0.9391 0.8985
SK-BR-3 MK2206
0.04
uM
LJP6
 2
F06
 72
hr
 1476 3442 3694 0.9318 0.8863
SK-BR-3 MK2206
0.04
uM
LJP6
 3
F06
 72
hr
 1476 3206 3694 0.8679 0.7799
SK-BR-3 Neratinib
0.04
uM
LJP5
 1
A18
 72
hr
 1476 1492 3694 0.4039 0.0069
SK-BR-3 Neratinib
0.04
uM
LJP5
 2
A18
 72
hr
 1476 1262 3694 0.3416 -0.0968
SK-BR-3 Neratinib
0.04
uM
LJP5
 3
A18
 72
hr
 1476 1292 3694 0.3498 -0.0833
SK-BR-3 Nilotinib
0.04
uM
LJP5
 1
N18
 72
hr
 1476 3754 3694 1.0162 1.0270
SK-BR-3 Nilotinib
0.04
uM
LJP5
 2
N18
 72
hr
 1476 3637 3694 0.9846 0.9743
SK-BR-3 Nilotinib
0.04
uM
LJP5
 3
N18
 72
hr
 1476 4045 3694 1.0950 1.1583
SK-BR-3 Nintedanib
0.04
uM
LJP6
 1
H06
 72
hr
 1476 3851 3694 1.0425 1.0708
SK-BR-3 Nintedanib
0.04
uM
LJP6
 2
H06
 72
hr
 1476 3910 3694 1.0585 1.0974
SK-BR-3 Nintedanib
0.04
uM
LJP6
 3
H06
 72
hr
 1476 3711 3694 1.0046 1.0076
SK-BR-3 NU7441
0.04
uM
LJP5
 1
C12
 72
hr
 1476 4009 3694 1.0853 1.1420
SK-BR-3 NU7441
0.04
uM
LJP5
 2
C12
 72
hr
 1476 4054 3694 1.0974 1.1623
SK-BR-3 NU7441
0.04
uM
LJP5
 3
C12
 72
hr
 1476 3832 3694 1.0373 1.0622
SK-BR-3 Dactolisib
0.04
uM
LJP5
 1
M18
 72
hr
 1476 1669 3694 0.4518 0.0867
SK-BR-3 Dactolisib
0.04
uM
LJP5
 2
M18
 72
hr
 1476 1723 3694 0.4664 0.1111
SK-BR-3 Dactolisib
0.04
uM
LJP5
 3
M18
 72
hr
 1476 2014 3694 0.5452 0.2423
SK-BR-3 NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 1476 3803 3694 1.0295 1.0491
SK-BR-3 NVP-TAE684
0.04
uM
LJP6
 2
K18
 72
hr
 1476 3996 3694 1.0817 1.1362
SK-BR-3 NVP-TAE684
0.04
uM
LJP6
 3
K18
 72
hr
 1476 3919 3694 1.0609 1.1015
SK-BR-3 Palbociclib
0.04
uM
LJP6
 1
E18
 72
hr
 1476 3496 3694 0.9464 0.9107
SK-BR-3 Palbociclib
0.04
uM
LJP6
 2
E18
 72
hr
 1476 3410 3694 0.9231 0.8719
SK-BR-3 Palbociclib
0.04
uM
LJP6
 3
E18
 72
hr
 1476 3554 3694 0.9621 0.9368