LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 AZD7762
10.0
uM
LJP6
 3
L01
 72
hr
 868 582 3486 0.1669 -0.1093
MDA-MB-231 AZD8055
10.0
uM
LJP6
 1
A07
 72
hr
 868 1102 3486 0.3161 0.0893
MDA-MB-231 AZD8055
10.0
uM
LJP6
 2
A07
 72
hr
 868 929 3486 0.2665 0.0233
MDA-MB-231 AZD8055
10.0
uM
LJP6
 3
A07
 72
hr
 868 910 3486 0.2610 0.0160
MDA-MB-231 AZD8330
10.0
uM
LJP5
 1
G19
 72
hr
 868 1071 3486 0.3072 0.0775
MDA-MB-231 AZD8330
10.0
uM
LJP5
 2
G19
 72
hr
 868 975 3486 0.2797 0.0408
MDA-MB-231 AZD8330
10.0
uM
LJP5
 3
G19
 72
hr
 868 1049 3486 0.3009 0.0691
MDA-MB-231 Barasertib
10.0
uM
LJP5
 1
D07
 72
hr
 868 1245 3486 0.3571 0.1439
MDA-MB-231 Barasertib
10.0
uM
LJP5
 2
D07
 72
hr
 868 1221 3486 0.3502 0.1348
MDA-MB-231 Barasertib
10.0
uM
LJP5
 3
D07
 72
hr
 868 1272 3486 0.3649 0.1543
MDA-MB-231 BI-2536
10.0
uM
LJP6
 1
D13
 72
hr
 868 1204 3486 0.3453 0.1283
MDA-MB-231 BI-2536
10.0
uM
LJP6
 2
D13
 72
hr
 868 1251 3486 0.3588 0.1462
MDA-MB-231 BI-2536
10.0
uM
LJP6
 3
D13
 72
hr
 868 1212 3486 0.3476 0.1313
MDA-MB-231 BMS345541
10.0
uM
LJP6
 1
D01
 72
hr
 868 715 3486 0.2051 -0.0585
MDA-MB-231 BMS345541
10.0
uM
LJP6
 2
D01
 72
hr
 868 781 3486 0.2240 -0.0333
MDA-MB-231 BMS345541
10.0
uM
LJP6
 3
D01
 72
hr
 868 778 3486 0.2232 -0.0344
MDA-MB-231 SNS-032
10.0
uM
LJP6
 1
H13
 72
hr
 868 687 3486 0.1971 -0.0692
MDA-MB-231 SNS-032
10.0
uM
LJP6
 2
H13
 72
hr
 868 866 3486 0.2484 -0.0008
MDA-MB-231 SNS-032
10.0
uM
LJP6
 3
H13
 72
hr
 868 794 3486 0.2277 -0.0283
MDA-MB-231 GDC-0980
10.0
uM
LJP5
 1
K19
 72
hr
 868 1426 3486 0.4090 0.2131
MDA-MB-231 GDC-0980
10.0
uM
LJP5
 2
K19
 72
hr
 868 1508 3486 0.4325 0.2444
MDA-MB-231 GDC-0980
10.0
uM
LJP5
 3
K19
 72
hr
 868 1379 3486 0.3955 0.1951
MDA-MB-231 NVP-AEW541
10.0
uM
LJP5
 1
E13
 72
hr
 868 1418 3486 0.4067 0.2100
MDA-MB-231 NVP-AEW541
10.0
uM
LJP5
 2
E13
 72
hr
 868 1160 3486 0.3327 0.1115
MDA-MB-231 NVP-AEW541
10.0
uM
LJP5
 3
E13
 72
hr
 868 1444 3486 0.4142 0.2200