LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 YM 201636
3.33
uM
LJP5
 2
N08
 72
hr
 868 2701 3486 0.7747 0.7000
MDA-MB-231 YM 201636
3.33
uM
LJP5
 3
N08
 72
hr
 868 2590 3486 0.7429 0.6576
MDA-MB-231 ZSTK474
3.33
uM
LJP6
 1
M14
 72
hr
 868 2174 3486 0.6236 0.4988
MDA-MB-231 ZSTK474
3.33
uM
LJP6
 2
M14
 72
hr
 868 2292 3486 0.6574 0.5438
MDA-MB-231 ZSTK474
3.33
uM
LJP6
 3
M14
 72
hr
 868 2132 3486 0.6115 0.4827
MDA-MB-231 Afatinib
10.0
uM
LJP6
 1
G19
 72
hr
 868 606 3486 0.1738 -0.1001
MDA-MB-231 Afatinib
10.0
uM
LJP6
 2
G19
 72
hr
 868 822 3486 0.2358 -0.0176
MDA-MB-231 Afatinib
10.0
uM
LJP6
 3
G19
 72
hr
 868 769 3486 0.2206 -0.0379
MDA-MB-231 Sigma A6730
10.0
uM
LJP5
 1
B19
 72
hr
 868 2040 3486 0.5851 0.4476
MDA-MB-231 Sigma A6730
10.0
uM
LJP5
 2
B19
 72
hr
 868 1777 3486 0.5097 0.3471
MDA-MB-231 Sigma A6730
10.0
uM
LJP5
 3
B19
 72
hr
 868 1921 3486 0.5510 0.4021
MDA-MB-231 Alvocidib
10.0
uM
LJP6
 1
A13
 72
hr
 868 743 3486 0.2131 -0.0478
MDA-MB-231 Alvocidib
10.0
uM
LJP6
 2
A13
 72
hr
 868 611 3486 0.1753 -0.0982
MDA-MB-231 Alvocidib
10.0
uM
LJP6
 3
A13
 72
hr
 868 648 3486 0.1859 -0.0841
MDA-MB-231 AT-7519
10.0
uM
LJP6
 1
K01
 72
hr
 868 481 3486 0.1380 -0.1479
MDA-MB-231 AT-7519
10.0
uM
LJP6
 2
K01
 72
hr
 868 523 3486 0.1500 -0.1318
MDA-MB-231 AT-7519
10.0
uM
LJP6
 3
K01
 72
hr
 868 655 3486 0.1879 -0.0814
MDA-MB-231 AZD 5438
10.0
uM
LJP6
 1
J01
 72
hr
 868 639 3486 0.1833 -0.0875
MDA-MB-231 AZD 5438
10.0
uM
LJP6
 2
J01
 72
hr
 868 659 3486 0.1890 -0.0799
MDA-MB-231 AZD 5438
10.0
uM
LJP6
 3
J01
 72
hr
 868 668 3486 0.1916 -0.0764
MDA-MB-231 AZD-6482
10.0
uM
LJP5
 1
I01
 72
hr
 868 1109 3486 0.3181 0.0920
MDA-MB-231 AZD-6482
10.0
uM
LJP5
 2
I01
 72
hr
 868 1233 3486 0.3537 0.1394
MDA-MB-231 AZD-6482
10.0
uM
LJP5
 3
I01
 72
hr
 868 1439 3486 0.4128 0.2180
MDA-MB-231 AZD7762
10.0
uM
LJP6
 1
L01
 72
hr
 868 673 3486 0.1930 -0.0745
MDA-MB-231 AZD7762
10.0
uM
LJP6
 2
L01
 72
hr
 868 645 3486 0.1850 -0.0852