LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 Momelotinib
3.33
uM
LJP5
 2
P08
 72
hr
 868 2136 3486 0.6127 0.4842
MDA-MB-231 Momelotinib
3.33
uM
LJP5
 3
P08
 72
hr
 868 1933 3486 0.5544 0.4067
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 1
D02
 72
hr
 868 488 3486 0.1400 -0.1452
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 2
D02
 72
hr
 868 510 3486 0.1463 -0.1368
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 3
D02
 72
hr
 868 547 3486 0.1569 -0.1227
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 1
I02
 72
hr
 868 407 3486 0.1167 -0.1761
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 2
I02
 72
hr
 868 504 3486 0.1446 -0.1391
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 3
I02
 72
hr
 868 470 3486 0.1348 -0.1521
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 1
E20
 72
hr
 868 1737 3486 0.4982 0.3319
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 2
E20
 72
hr
 868 1642 3486 0.4710 0.2956
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 3
E20
 72
hr
 868 1569 3486 0.4500 0.2677
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 1
D14
 72
hr
 868 3555 3486 1.0197 1.0262
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 2
D14
 72
hr
 868 3122 3486 0.8955 0.8608
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 3
D14
 72
hr
 868 3772 3486 1.0819 1.1091
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 1
M20
 72
hr
 868 3212 3486 0.9213 0.8952
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 2
M20
 72
hr
 868 3565 3486 1.0225 1.0300
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 3
M20
 72
hr
 868 3291 3486 0.9440 0.9254
MDA-MB-231 Foretinib
3.33
uM
LJP5
 1
H08
 72
hr
 868 1312 3486 0.3763 0.1695
MDA-MB-231 Foretinib
3.33
uM
LJP5
 2
H08
 72
hr
 868 1398 3486 0.4010 0.2024
MDA-MB-231 Foretinib
3.33
uM
LJP5
 3
H08
 72
hr
 868 1457 3486 0.4179 0.2249
MDA-MB-231 R406
3.33
uM
LJP6
 1
C14
 72
hr
 868 2515 3486 0.7214 0.6290
MDA-MB-231 R406
3.33
uM
LJP6
 2
C14
 72
hr
 868 2425 3486 0.6956 0.5946
MDA-MB-231 R406
3.33
uM
LJP6
 3
C14
 72
hr
 868 2376 3486 0.6815 0.5759
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 1
D20
 72
hr
 868 2648 3486 0.7595 0.6798
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 2
D20
 72
hr
 868 2612 3486 0.7492 0.6660