LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MDA-MB-231 OSI-027
3.33
uM
LJP6
 3
E08
 72
hr
 868 2131 3486 0.6112 0.4823
MDA-MB-231 XMD11-85h
3.33
uM
LJP6
 1
P20
 72
hr
 868 2420 3486 0.6941 0.5927
MDA-MB-231 XMD11-85h
3.33
uM
LJP6
 2
P20
 72
hr
 868 2553 3486 0.7323 0.6435
MDA-MB-231 XMD11-85h
3.33
uM
LJP6
 3
P20
 72
hr
 868 2398 3486 0.6878 0.5843
MDA-MB-231 HG-6-64-01
3.33
uM
LJP6
 1
M02
 72
hr
 868 870 3486 0.2495 0.0007
MDA-MB-231 HG-6-64-01
3.33
uM
LJP6
 2
M02
 72
hr
 868 1037 3486 0.2974 0.0645
MDA-MB-231 HG-6-64-01
3.33
uM
LJP6
 3
M02
 72
hr
 868 1228 3486 0.3522 0.1375
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 1
O08
 72
hr
 868 793 3486 0.2275 -0.0287
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 2
O08
 72
hr
 868 815 3486 0.2338 -0.0203
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 3
O08
 72
hr
 868 826 3486 0.2369 -0.0161
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 1
J20
 72
hr
 868 2669 3486 0.7656 0.6878
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 2
J20
 72
hr
 868 2491 3486 0.7145 0.6198
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 3
J20
 72
hr
 868 2456 3486 0.7045 0.6065
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 1
M08
 72
hr
 868 1172 3486 0.3362 0.1161
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 2
M08
 72
hr
 868 1362 3486 0.3907 0.1886
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 3
M08
 72
hr
 868 1221 3486 0.3502 0.1348
MDA-MB-231 Brivanib
3.33
uM
LJP5
 1
P14
 72
hr
 868 2335 3486 0.6698 0.5603
MDA-MB-231 Brivanib
3.33
uM
LJP5
 2
P14
 72
hr
 868 3258 3486 0.9345 0.9128
MDA-MB-231 Brivanib
3.33
uM
LJP5
 3
P14
 72
hr
 868 2755 3486 0.7902 0.7207
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 1
H02
 72
hr
 868 1139 3486 0.3267 0.1035
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 2
H02
 72
hr
 868 1072 3486 0.3075 0.0779
MDA-MB-231 Buparlisib
3.33
uM
LJP5
 3
H02
 72
hr
 868 1195 3486 0.3428 0.1249
MDA-MB-231 BX-912
3.33
uM
LJP5
 1
L20
 72
hr
 868 1404 3486 0.4027 0.2047
MDA-MB-231 BX-912
3.33
uM
LJP5
 2
L20
 72
hr
 868 1574 3486 0.4515 0.2696
MDA-MB-231 BX-912
3.33
uM
LJP5
 3
L20
 72
hr
 868 1376 3486 0.3947 0.1940