Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 88.5 58
N2645 PH-797804 0.6
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 53.5 62
RA2708 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 59.0 57
RA2708 PH-797804 0.6
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 71.0 53
RA2159 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 99.0 75
N2645 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 78.0 77
RA2708 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 79.5 56
RA2159 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 75.5 58
RA2159 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 66.5 58
N2645 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 85.0 59
N2645 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 49.0 62
RA2708 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 75.0 59
RA2708 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 63.0 66
RA2159 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 54.0 58
N2645 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 59.5 52
RA2708 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 77.0 62
RA2159 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 59.0 78
RA2159 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 64.5 60
N2645 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 60.0 65
N2645 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 47.0 63
RA2708 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 55.0 63
RA2708 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 54.5 52
RA2159 2
IL-12 (p70)
 51.0 58
N2645 2
IL-12 (p70)
 69.0 57
RA2708 2
IL-12 (p70)
 50.5 54