Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 JNK-IN-8 3.0
uM
 2
IL-12 (p70)
 69.0 67
RA2159 PH-797804 0.6
uM
 2
IL-12 (p70)
 57.0 66
N2645 JNK-IN-8 3.0
uM
 2
IL-12 (p70)
 52.0 69
N2645 PH-797804 0.6
uM
 2
IL-12 (p70)
 45.0 60
RA2708 JNK-IN-8 3.0
uM
 2
IL-12 (p70)
 50.0 63
RA2708 PH-797804 0.6
uM
 2
IL-12 (p70)
 53.0 61
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL-12 (p70)
 49.0 69
RA2159 IKK16 2.0
uM
 2
IL-12 (p70)
 44.5 54
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-12 (p70)
 46.5 66
N2645 IKK16 2.0
uM
 2
IL-12 (p70)
 37.0 59
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-12 (p70)
 56.0 65
RA2708 IKK16 2.0
uM
 2
IL-12 (p70)
 33.0 63
RA2159 Tofacitinib 0.3
uM
 2
IL-12 (p70)
 64.0 74
RA2159 2
IL-12 (p70)
 55.5 64
N2645 Tofacitinib 0.3
uM
 2
IL-12 (p70)
 48.0 71
N2645 2
IL-12 (p70)
 54.0 69
RA2708 Tofacitinib 0.3
uM
 2
IL-12 (p70)
 51.0 56
RA2708 2
IL-12 (p70)
 73.0 50
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 57.5 54
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 71.0 53
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 62.0 67
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 80.0 55
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 57.0 51
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 53.0 66
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 68.0 48