JNK-IN-8 - Small Molecule (ID:10363-101)
| HMS LINCS ID: |
10363-101
|
| Name: | JNK-IN-8 |
| Alternative Names: | JNK Inhibitor XVI |
| LINCS ID: | LSM-44525 |
| PubChem CID: | 76516568 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 507.24 |
| InChi: | InChI=1S/C29H29N7O2/c1-20-17-24(11-12-25(20)34-29-31-15-13-26(35-29)22-8-5-14-30-19-22)33-28(38)21-7-4-9-23(18-21)32-27(37)10-6-16-36(2)3/h4-15,17-19H,16H2,1-3H3,(H,32,37)(H,33,38)(H,31,34,35) |
| InChi Key: | GJFCSAPFHAXMSF-UHFFFAOYSA-N |
| SMILES: | CC1=C(C=CC(=C1)NC(=O)C2=CC(=CC=C2)NC(=O)C=CCN(C)C)NC3=NC=CC(=N3)C4=CN=CC=C4 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2018-03-30 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
MAPK8, MAPK9 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | MAPK10, PRKX |
10 (confirmed non-binding) |
Batch Information for HMSL10363-101-2:
| HMS LINCS Batch ID: | 10363-101-2 |
| Provider: | Nathanael Gray (DFCI) |
| Provider Batch ID: | |
| Salt: | 101 |
| Molecular Formula: | |
| Molecular Weight: | |
| Purity: | |
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| Comments: | |
| Date Publicly Available: | 2015-06-26 |
| Most Recent Update: | 2016-12-02 |
(Kd <100 nM)