Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 TNF-a 100
ng/mL
 4
IL-7
 18.0 63
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-7
 23.0 74
RA2708 TNF-a 100
ng/mL
 4
IL-7
 18.0 37
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-7
 49.5 72
RA2159 IKK16 2.0
uM
 4
IL-7
 54.0 77
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL-7
 14.0 53
N2645 IKK16 2.0
uM
 4
IL-7
 18.0 53
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL-7
 24.0 70
RA2708 IKK16 2.0
uM
 4
IL-7
 16.5 56
RA2159 Tofacitinib 0.3
uM
 4
IL-7
 47.0 59
RA2159 4
IL-7
 54.0 57
N2645 Tofacitinib 0.3
uM
 4
IL-7
 15.0 53
N2645 4
IL-7
 13.0 55
RA2708 Tofacitinib 0.3
uM
 4
IL-7
 22.0 61
RA2708 4
IL-7
 15.0 55
RA2159 4
IL-7
 54.0 53
N2645 4
IL-7
 12.5 52
RA2708 4
IL-7
 18.0 77
RA2159 JNK-IN-8 3.0
uM
 4
IL-7
 48.0 49
RA2159 PH-797804 0.6
uM
 4
IL-7
 52.0 75
N2645 JNK-IN-8 3.0
uM
 4
IL-7
 15.0 61
N2645 PH-797804 0.6
uM
 4
IL-7
 15.5 54
RA2708 JNK-IN-8 3.0
uM
 4
IL-7
 20.0 66
RA2708 PH-797804 0.6
uM
 4
IL-7
 17.0 69
RA2159 Poly(I:C) 2
ug/mL
 4
IL-7
 57.0 61