Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 JNK-IN-8 3.0
uM
 3
TNF-a
 19.0 51
N2759 PH-797804 0.6
uM
 3
TNF-a
 21.0 57
RA1931 JNK-IN-8 3.0
uM
 3
TNF-a
 17.0 62
RA1931 PH-797804 0.6
uM
 3
TNF-a
 20.0 66
N2586 JNK-IN-8 3.0
uM
 3
TNF-a
 21.0 63
N2586 PH-797804 0.6
uM
 3
TNF-a
 20.0 48
0
TNF-a
 20.5 22
0
TNF-a
 22.0 27
0
TNF-a
 26.0 15
RA2159 5z-7-oxozeaenol 0.6
uM
 4
TNF-a
 21.5 26
RA2159 IKK16 2.0
uM
 4
TNF-a
 23.0 40
N2645 5z-7-oxozeaenol 0.6
uM
 4
TNF-a
 22.0 42
N2645 IKK16 2.0
uM
 4
TNF-a
 26.0 54
RA2708 5z-7-oxozeaenol 0.6
uM
 4
TNF-a
 25.0 45
RA2708 IKK16 2.0
uM
 4
TNF-a
 24.0 49
RA2159 Tofacitinib 0.3
uM
 4
TNF-a
 23.0 34
RA2159 4
TNF-a
 25.5 44
N2645 Tofacitinib 0.3
uM
 4
TNF-a
 21.5 34
N2645 4
TNF-a
 23.5 16
RA2708 Tofacitinib 0.3
uM
 4
TNF-a
 23.0 25
RA2708 4
TNF-a
 20.5 32
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 26.0 38
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 35.0 37
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 20.0 32
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 23.0 40