Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 24.0 41
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 34.5 40
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 61.5 36
RA2159 Poly(I:C) 2
ug/mL
 4
TNF-a
 72.0 27
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 25.5 30
N2645 Poly(I:C) 2
ug/mL
 4
TNF-a
 35.0 29
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 81.0 29
RA2708 Poly(I:C) 2
ug/mL
 4
TNF-a
 82.0 33
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 20.5 30
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 32.0 53
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 20.5 42
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 29.0 41
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 20.0 34
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 44.5 24
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 88.5 32
RA2159 IL-1 alpha 100
ng/mL
 4
TNF-a
 86.0 25
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 46.0 29
N2645 IL-1 alpha 100
ng/mL
 4
TNF-a
 60.5 28
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 96.0 31
RA2708 IL-1 alpha 100
ng/mL
 4
TNF-a
 85.0 25
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TNF-a
 25467.0 41
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
TNF-a
 23733.0 52
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TNF-a
 21747.0 37
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
TNF-a
 18507.0 41
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TNF-a
 24999.5 52