Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 150.0 57
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 114.0 48
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 121.0 64
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 630.0 55
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 159.0 56
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 144.5 54
RA2159 TNF-a 100
ng/mL
 2
FGF Basic
 151.0 57
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 138.5 58
N2645 TNF-a 100
ng/mL
 2
FGF Basic
 135.0 58
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 130.0 41
RA2708 TNF-a 100
ng/mL
 2
FGF Basic
 137.0 33
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 57.0 69
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 63.0 52
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 54.0 62
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 65.0 58
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 56.5 64
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 70.0 62
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 106.5 64
RA2159 IL-1 alpha 100
ng/mL
 2
FGF Basic
 95.0 60
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 69.0 50
N2645 IL-1 alpha 100
ng/mL
 2
FGF Basic
 65.0 49
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 98.0 49
RA2708 IL-1 alpha 100
ng/mL
 2
FGF Basic
 96.5 50
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
FGF Basic
 53.0 53
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
FGF Basic
 64.0 61