Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
0
IL-12 (p70)
15.0 51
0
IL-12 (p70)
13.0 66
0
IL-12 (p70)
15.0 38
RA1869 3
IL-12 (p70)
94.5 60
N2759 3
IL-12 (p70)
63.0 75
RA1931 3
IL-12 (p70)
66.0 62
N2586 3
IL-12 (p70)
58.0 61
RA1869 JNK-IN-8 3.0
uM
3
IL-12 (p70)
63.5 62
RA1869 PH-797804 0.6
uM
3
IL-12 (p70)
81.0 60
N2759 JNK-IN-8 3.0
uM
3
IL-12 (p70)
53.5 52
N2759 PH-797804 0.6
uM
3
IL-12 (p70)
49.0 56
RA1931 JNK-IN-8 3.0
uM
3
IL-12 (p70)
61.5 66
RA1931 PH-797804 0.6
uM
3
IL-12 (p70)
78.5 60
N2586 JNK-IN-8 3.0
uM
3
IL-12 (p70)
53.0 53
N2586 PH-797804 0.6
uM
3
IL-12 (p70)
75.0 35
0
IL-12 (p70)
17.0 21
0
IL-12 (p70)
13.0 10
0
IL-12 (p70)
21.0 20
RA2159 5z-7-oxozeaenol 0.6
uM
4
IL-12 (p70)
53.5 26
RA2159 IKK16 2.0
uM
4
IL-12 (p70)
63.0 42
N2645 5z-7-oxozeaenol 0.6
uM
4
IL-12 (p70)
30.5 44
N2645 IKK16 2.0
uM
4
IL-12 (p70)
44.0 39
RA2708 5z-7-oxozeaenol 0.6
uM
4
IL-12 (p70)
74.0 27
RA2708 IKK16 2.0
uM
4
IL-12 (p70)
59.0 32
RA2159 Tofacitinib 0.3
uM
4
IL-12 (p70)
74.0 32