Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 1
IL-12 (p70)
76.0 50
RA1931 Tofacitinib 0.3
uM
1
IL-12 (p70)
112.0 57
RA1931 1
IL-12 (p70)
92.0 45
N2586 Tofacitinib 0.3
uM
1
IL-12 (p70)
82.0 45
N2586 1
IL-12 (p70)
76.0 29
0
IL-12 (p70)
20.0 34
0
IL-12 (p70)
19.0 45
0
IL-12 (p70)
17.0 49
0
IL-12 (p70)
24.0 71
0
IL-12 (p70)
18.5 46
0
IL-12 (p70)
20.5 46
RA2159 2
IL-12 (p70)
80.0 70
N2645 2
IL-12 (p70)
50.5 54
RA2708 2
IL-12 (p70)
60.0 65
RA2159 JNK-IN-8 3.0
uM
2
IL-12 (p70)
41.5 58
RA2159 PH-797804 0.6
uM
2
IL-12 (p70)
56.0 52
N2645 JNK-IN-8 3.0
uM
2
IL-12 (p70)
40.0 69
N2645 PH-797804 0.6
uM
2
IL-12 (p70)
30.0 58
RA2708 JNK-IN-8 3.0
uM
2
IL-12 (p70)
53.5 54
RA2708 PH-797804 0.6
uM
2
IL-12 (p70)
42.0 47
RA2159 TNF-a 100
ng/mL
2
IL-12 (p70)
64.0 61
N2645 TNF-a 100
ng/mL
2
IL-12 (p70)
43.5 70
RA2708 TNF-a 100
ng/mL
2
IL-12 (p70)
57.0 54
RA2159 JNK-IN-8 3.0
uM
TNF-a 100
ng/mL
2
IL-12 (p70)
49.0 80
RA2159 PH-797804 0.6
uM
TNF-a 100
ng/mL
2
IL-12 (p70)
51.0 63