Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 40.0 45
N2645 PH-797804 0.6
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 36.5 52
RA2708 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 62.5 72
RA2708 PH-797804 0.6
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 43.0 59
RA2159 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 78.5 36
N2645 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 57.0 74
RA2708 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 71.0 57
RA2159 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 55.5 80
RA2159 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 54.0 65
N2645 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 42.0 50
N2645 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 35.0 54
RA2708 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 67.5 54
RA2708 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 49.0 41
RA2159 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 51.0 51
N2645 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 39.0 61
RA2708 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 56.0 81
RA2159 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 44.0 70
RA2159 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 48.5 66
N2645 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 32.0 53
N2645 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 30.0 55
RA2708 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 50.5 44
RA2708 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 40.5 36
RA2159 2
IL-12 (p70)
 50.0 51
N2645 2
IL-12 (p70)
 38.0 62
RA2708 2
IL-12 (p70)
 42.0 53