Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 TNF-a 100
ng/mL
 4
IL-7
 17.0 37
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-7
 12.0 26
RA2708 TNF-a 100
ng/mL
 4
IL-7
 17.0 27
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-7
 73.0 23
RA2159 IKK16 2.0
uM
 4
IL-7
 113.5 40
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL-7
 8.5 34
N2645 IKK16 2.0
uM
 4
IL-7
 13.5 48
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL-7
 17.0 32
RA2708 IKK16 2.0
uM
 4
IL-7
 18.0 43
RA2159 Tofacitinib 0.3
uM
 4
IL-7
 57.0 29
RA2159 4
IL-7
 55.0 36
N2645 Tofacitinib 0.3
uM
 4
IL-7
 12.5 30
N2645 4
IL-7
 15.0 38
RA2708 Tofacitinib 0.3
uM
 4
IL-7
 28.0 36
RA2708 4
IL-7
 20.0 31
RA2159 4
IL-7
 47.0 28
N2645 4
IL-7
 12.0 37
RA2708 4
IL-7
 13.0 39
RA2159 JNK-IN-8 3.0
uM
 4
IL-7
 77.0 32
RA2159 PH-797804 0.6
uM
 4
IL-7
 54.5 32
N2645 JNK-IN-8 3.0
uM
 4
IL-7
 12.0 35
N2645 PH-797804 0.6
uM
 4
IL-7
 9.0 28
RA2708 JNK-IN-8 3.0
uM
 4
IL-7
 16.0 33
RA2708 PH-797804 0.6
uM
 4
IL-7
 21.0 29
RA2159 Poly(I:C) 2
ug/mL
 4
IL-7
 51.0 19