Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IFN-a2
 21.0 44
RA2708 IKK16 2.0
uM
 2
IFN-a2
 24.0 67
RA2159 Tofacitinib 0.3
uM
 2
IFN-a2
 22.0 62
RA2159 2
IFN-a2
 21.0 62
N2645 Tofacitinib 0.3
uM
 2
IFN-a2
 21.5 62
N2645 2
IFN-a2
 22.5 66
RA2708 Tofacitinib 0.3
uM
 2
IFN-a2
 21.0 54
RA2708 2
IFN-a2
 22.0 51
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IFN-a2
 21.0 56
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IFN-a2
 24.5 72
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IFN-a2
 20.0 58
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IFN-a2
 21.0 66
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IFN-a2
 19.0 64
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IFN-a2
 21.0 67
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IFN-a2
 22.5 46
RA2159 TNF-a 100
ng/mL
 2
IFN-a2
 22.0 55
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IFN-a2
 22.0 69
N2645 TNF-a 100
ng/mL
 2
IFN-a2
 23.0 66
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IFN-a2
 24.0 36
RA2708 TNF-a 100
ng/mL
 2
IFN-a2
 22.0 43
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IFN-a2
 33.0 45
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IFN-a2
 35.0 56
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IFN-a2
 36.0 50
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IFN-a2
 31.5 48
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IFN-a2
 32.5 54