Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
TNFb
 37.5 50
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
TNFb
 35.5 82
N2586 Sigma A6730 3.0
uM
 3
TNFb
 43.5 56
RA2159 IL-1 alpha 100
ng/mL
 3
TNFb
 51.0 50
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 57.0 60
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 57.0 50
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 76.0 51
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 65.0 56
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 60.5 46
RA2159 PI103 0.1
uM
 3
TNFb
 39.0 68
N2586 IL-1 alpha 100
ng/mL
 3
TNFb
 86.0 63
N2586 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 54.5 50
N2586 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 48.0 55
N2586 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 61.5 56
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 56.5 48
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 49.0 61
N2586 PI103 0.1
uM
 3
TNFb
 31.5 50
0
TNFb
 57.0 63
RA2159 TNF-a 100
ng/mL
 3
TNFb
 318.5 54
RA2159 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
TNFb
 58.0 55
RA2159 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
TNFb
 48.0 66
RA2159 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
TNFb
 30.5 46
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
TNFb
 46.0 56
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
TNFb
 51.0 40
RA2159 EO1428 1.0
uM
 3
TNFb
 41.0 35