Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 PI103 0.1
uM
 IL-6 100
ug/mL
 2
TNFb
 55.0 58
N2586 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
TNFb
 46.0 65
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
TNFb
 39.0 43
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
TNFb
 44.5 54
N2586 Ruxolitinib 0.3
uM
 2
TNFb
 61.5 54
RA2159 IL-17A 100
ng/mL
 2
TNFb
 49.0 64
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
TNFb
 45.0 59
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
TNFb
 45.5 54
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
TNFb
 58.0 75
RA2159 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
TNFb
 41.0 65
RA2159 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
TNFb
 35.0 23
RA2159 Tofacitinib 0.3
uM
 2
TNFb
 37.5 34
N2586 IL-17A 100
ng/mL
 2
TNFb
 46.0 40
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
TNFb
 79.0 71
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
TNFb
 44.5 12
N2586 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
TNFb
 56.0 29
N2586 JNK-IN-8 3.0
uM
 IL-17A 100
ng/mL
 2
TNFb
 55.5 40
N2586 JNK-IN-11 0.3
uM
 IL-17A 100
ng/mL
 2
TNFb
 80.0 59
N2586 Tofacitinib 0.3
uM
 2
TNFb
 61.0 57
RA2159 2
TNFb
 34.0 61
RA2159 EO1428 1.0
uM
 2
TNFb
 46.0 49
RA2159 PI103 0.1
uM
 2
TNFb
 50.0 42
RA2159 Sigma A6730 3.0
uM
 2
TNFb
 44.0 33
RA2159 JNK-IN-8 3.0
uM
 2
TNFb
 42.5 50
RA2159 JNK-IN-11 0.3
uM
 2
TNFb
 39.0 54