Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 TNF-a 100
ng/mL
 3
TNFb
 33.5 52
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 3
TNFb
 80.0 87
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 3
TNFb
 36.0 50
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
TNFb
 35.5 66
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
TNFb
 83.0 69
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
TNFb
 39.0 50
N2586 EO1428 1.0
uM
 3
TNFb
 122.0 39
0
TNFb
 51.0 55
RA2159 3
TNFb
 44.0 53
RA2159 PD184352 0.1
uM
 3
TNFb
 46.0 52
RA2159 Lestaurtinib 0.3
uM
 3
TNFb
 84.0 41
RA2159 Ruxolitinib 0.3
uM
 3
TNFb
 52.5 42
RA2159 Tofacitinib 0.3
uM
 3
TNFb
 36.0 62
RA2159 IKK16 2.0
uM
 3
TNFb
 46.0 43
RA2159 3
TNFb
 87.5 68
N2586 3
TNFb
 57.0 47
N2586 PD184352 0.1
uM
 3
TNFb
 34.0 41
N2586 Lestaurtinib 0.3
uM
 3
TNFb
 33.0 45
N2586 Ruxolitinib 0.3
uM
 3
TNFb
 48.5 58
N2586 Tofacitinib 0.3
uM
 3
TNFb
 38.0 51
N2586 IKK16 2.0
uM
 3
TNFb
 47.0 23
N2586 3
TNFb
 54.0 59
0
TNFb
 38.0 51
RA2159 Poly(I:C) 2
ug/mL
 4
TNFb
 112.5 50
RA2159 EO1428 1.0
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 103.0 58