Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 IKK16 2.0
uM
 3
TNFb
 39.0 54
N2586 JNK-IN-8 3.0
uM
 3
TNFb
 39.0 55
RA2159 IL-17A 100
ng/mL
 3
TNFb
 56.0 73
RA2159 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
TNFb
 44.0 76
RA2159 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
TNFb
 44.0 59
RA2159 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
TNFb
 37.5 72
RA2159 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
TNFb
 33.0 49
RA2159 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
TNFb
 37.0 49
N2586 IL-17A 100
ng/mL
 3
TNFb
 45.0 66
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
TNFb
 37.5 52
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
TNFb
 37.0 53
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
TNFb
 121.0 46
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
TNFb
 40.0 68
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
TNFb
 34.0 42
RA2159 IL-6 100
ug/mL
 3
TNFb
 37.0 52
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
TNFb
 40.5 78
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
TNFb
 37.0 43
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
TNFb
 25.0 55
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
TNFb
 35.0 47
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
TNFb
 36.0 46
RA2159 Sigma A6730 3.0
uM
 3
TNFb
 44.0 61
N2586 IL-6 100
ug/mL
 3
TNFb
 89.0 70
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
TNFb
 29.5 46
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
TNFb
 29.0 41
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
TNFb
 33.0 60