Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-11 0.3
uM
 2
IL12(p40)
 56.0 41
N2586 2
IL12(p40)
 82.0 65
0
IL12(p40)
 64.5 52
0
IL12(p40)
 60.5 64
RA2159 TNF-a 100
ng/mL
 2
IL12(p40)
 67.0 59
RA2159 EO1428 1.0
uM
 TNF-a 100
ng/mL
 2
IL12(p40)
 70.5 62
RA2159 PI103 0.1
uM
 TNF-a 100
ng/mL
 2
IL12(p40)
 76.0 53
RA2159 Sigma A6730 3.0
uM
 TNF-a 100
ng/mL
 2
IL12(p40)
 68.0 50
RA2159 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 2
IL12(p40)
 64.0 54
RA2159 JNK-IN-11 0.3
uM
 TNF-a 100
ng/mL
 2
IL12(p40)
 62.0 59
RA2159 PD184352 0.1
uM
 2
IL12(p40)
 64.0 51
N2586 TNF-a 100
ng/mL
 2
IL12(p40)
 73.0 34
N2586 EO1428 1.0
uM
 TNF-a 100
ng/mL
 2
IL12(p40)
 64.0 73
N2586 PI103 0.1
uM
 TNF-a 100
ng/mL
 2
IL12(p40)
 71.0 59
N2586 Sigma A6730 3.0
uM
 TNF-a 100
ng/mL
 2
IL12(p40)
 70.5 36
N2586 JNK-IN-8 3.0
uM
 TNF-a 100
ng/mL
 2
IL12(p40)
 69.0 54
N2586 JNK-IN-11 0.3
uM
 TNF-a 100
ng/mL
 2
IL12(p40)
 59.0 43
N2586 PD184352 0.1
uM
 2
IL12(p40)
 78.0 45
RA2159 IL-1 alpha 100
ng/mL
 2
IL12(p40)
 72.0 66
RA2159 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 2
IL12(p40)
 66.5 60
RA2159 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 2
IL12(p40)
 67.0 71
RA2159 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL12(p40)
 70.0 64
RA2159 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL12(p40)
 64.0 54
RA2159 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL12(p40)
 65.0 58
RA2159 Lestaurtinib 0.3
uM
 2
IL12(p40)
 65.0 69