Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 IL-17A 100
ng/mL
 3
MIF
 63.0 50
N2586 PD184352 0.1
uM
 IL-17A 100
ng/mL
 3
MIF
 63.5 58
N2586 Lestaurtinib 0.3
uM
 IL-17A 100
ng/mL
 3
MIF
 47.0 75
N2586 Ruxolitinib 0.3
uM
 IL-17A 100
ng/mL
 3
MIF
 92.0 76
N2586 Tofacitinib 0.3
uM
 IL-17A 100
ng/mL
 3
MIF
 49.0 51
N2586 IKK16 2.0
uM
 IL-17A 100
ng/mL
 3
MIF
 45.0 53
RA2159 IL-6 100
ug/mL
 3
MIF
 18.5 68
RA2159 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
MIF
 21.0 64
RA2159 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
MIF
 21.0 52
RA2159 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
MIF
 22.0 50
RA2159 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
MIF
 18.0 66
RA2159 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
MIF
 20.0 54
RA2159 Sigma A6730 3.0
uM
 3
MIF
 23.0 62
N2586 IL-6 100
ug/mL
 3
MIF
 58.0 57
N2586 PD184352 0.1
uM
 IL-6 100
ug/mL
 3
MIF
 62.0 55
N2586 Lestaurtinib 0.3
uM
 IL-6 100
ug/mL
 3
MIF
 43.0 66
N2586 Ruxolitinib 0.3
uM
 IL-6 100
ug/mL
 3
MIF
 52.0 50
N2586 Tofacitinib 0.3
uM
 IL-6 100
ug/mL
 3
MIF
 51.0 55
N2586 IKK16 2.0
uM
 IL-6 100
ug/mL
 3
MIF
 42.0 54
N2586 Sigma A6730 3.0
uM
 3
MIF
 46.0 51
RA2159 IL-1 alpha 100
ng/mL
 3
MIF
 41.0 53
RA2159 PD184352 0.1
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 43.0 61
RA2159 Lestaurtinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 55.0 63
RA2159 Ruxolitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 51.0 39
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 45.0 67