Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 IL-1 alpha 100
ng/mL
 2
IL12(p40)
 74.0 61
N2586 EO1428 1.0
uM
 IL-1 alpha 100
ng/mL
 2
IL12(p40)
 75.0 71
N2586 PI103 0.1
uM
 IL-1 alpha 100
ng/mL
 2
IL12(p40)
 69.0 55
N2586 Sigma A6730 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL12(p40)
 74.0 49
N2586 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IL12(p40)
 82.0 57
N2586 JNK-IN-11 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL12(p40)
 61.0 31
N2586 Lestaurtinib 0.3
uM
 2
IL12(p40)
 74.0 60
RA2159 IL-6 100
ug/mL
 2
IL12(p40)
 161.0 60
RA2159 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
IL12(p40)
 57.0 53
RA2159 PI103 0.1
uM
 IL-6 100
ug/mL
 2
IL12(p40)
 123.0 59
RA2159 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
IL12(p40)
 60.0 68
RA2159 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
IL12(p40)
 56.0 53
RA2159 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
IL12(p40)
 56.0 32
RA2159 Ruxolitinib 0.3
uM
 2
IL12(p40)
 61.0 80
N2586 IL-6 100
ug/mL
 2
IL12(p40)
 56.0 57
N2586 EO1428 1.0
uM
 IL-6 100
ug/mL
 2
IL12(p40)
 58.5 74
N2586 PI103 0.1
uM
 IL-6 100
ug/mL
 2
IL12(p40)
 63.0 66
N2586 Sigma A6730 3.0
uM
 IL-6 100
ug/mL
 2
IL12(p40)
 73.0 50
N2586 JNK-IN-8 3.0
uM
 IL-6 100
ug/mL
 2
IL12(p40)
 60.0 46
N2586 JNK-IN-11 0.3
uM
 IL-6 100
ug/mL
 2
IL12(p40)
 60.0 58
N2586 Ruxolitinib 0.3
uM
 2
IL12(p40)
 63.0 73
RA2159 IL-17A 100
ng/mL
 2
IL12(p40)
 67.5 54
RA2159 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
IL12(p40)
 59.0 57
RA2159 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
IL12(p40)
 62.0 49
RA2159 Sigma A6730 3.0
uM
 IL-17A 100
ng/mL
 2
IL12(p40)
 76.0 74