Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20219)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | 2nd Drug | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Image | Measured Protein (Alexa Fluor 488) | Measured Protein Value (488) | Measured Protein (Alexa Fluor 568) | Measured Protein Value (568) | Measured Protein (Alexa Fluor 647) | Measured Protein Value (647) | Replicate | Plate Name | Plate Well |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| JNK-IN-8 | LOXIMVI | 2.0000 | uM | 24 | hr | | Ki-67 | 3123.80 | p-Rb(S807/S811) | 257.55 | p-cJun(S73) | 54.72 | 1 | LOXIMVI-signal3 | D3 | |
| JNK-IN-8 | LOXIMVI | 0.0000 | uM | 24 | hr | | Ki-67 | 3098.40 | p-Rb(S807/S811) | 213.41 | p-cJun(S73) | 128.11 | 1 | LOXIMVI-signal3 | D11 | |
| JNK-IN-8 | LOXIMVI | 2.0000 | uM | 24 | hr | | Ki-67 | 3091.80 | p-Rb(S807/S811) | 251.41 | p-cJun(S73) | 53.20 | 2 | LOXIMVI-signal3 | E3 | |
| Vemurafenib | LOXIMVI | 0.0000 | uM | 24 | hr | | Ki-67 | 3070.70 | p-Rb(S807/S811) | 206.62 | p-cJun(S73) | 122.85 | 1 | LOXIMVI-signal3 | B11 | |
| JNK-IN-8 | LOXIMVI | 0.0205 | uM | 24 | hr | | Ki-67 | 3052.30 | p-Rb(S807/S811) | 224.01 | p-cJun(S73) | 90.47 | 1 | LOXIMVI-signal3 | D8 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0000 | uM | 24 | hr | | Ki-67 | 3032.30 | p-Rb(S807/S811) | 209.50 | p-cJun(S73) | 127.94 | 1 | LOXIMVI-signal3 | F11 |
| JNK-IN-8 | LOXIMVI | 0.0000 | uM | 24 | hr | | Ki-67 | 3030.30 | p-Rb(S807/S811) | 205.20 | p-cJun(S73) | 122.59 | 2 | LOXIMVI-signal3 | E11 | |
| JNK-IN-8 | LOXIMVI | 0.8000 | uM | 24 | hr | | Ki-67 | 3017.80 | p-Rb(S807/S811) | 223.34 | p-cJun(S73) | 56.18 | 2 | LOXIMVI-signal3 | E4 | |
| JNK-IN-8 | LOXIMVI | 5.0000 | uM | 24 | hr | | Ki-67 | 3004.40 | p-Rb(S807/S811) | 244.06 | p-cJun(S73) | 51.77 | 1 | LOXIMVI-signal3 | D2 | |
| Vemurafenib | LOXIMVI | 0.0000 | uM | 24 | hr | | Ki-67 | 3001.50 | p-Rb(S807/S811) | 195.98 | p-cJun(S73) | 118.37 | 2 | LOXIMVI-signal3 | C11 | |
| Vemurafenib | LOXIMVI | 0.0082 | uM | 24 | hr | | Ki-67 | 2983.70 | p-Rb(S807/S811) | 203.05 | p-cJun(S73) | 109.97 | 2 | LOXIMVI-signal3 | C9 | |
| JNK-IN-8 | LOXIMVI | 0.0205 | uM | 24 | hr | | Ki-67 | 2981.20 | p-Rb(S807/S811) | 212.09 | p-cJun(S73) | 82.93 | 2 | LOXIMVI-signal3 | E8 | |
| JNK-IN-8 | LOXIMVI | 5.0000 | uM | 24 | hr | | Ki-67 | 2973.70 | p-Rb(S807/S811) | 240.23 | p-cJun(S73) | 48.04 | 2 | LOXIMVI-signal3 | E2 | |
| JNK-IN-8 | LOXIMVI | 0.8000 | uM | 24 | hr | | Ki-67 | 2971.40 | p-Rb(S807/S811) | 219.05 | p-cJun(S73) | 57.05 | 1 | LOXIMVI-signal3 | D4 | |
| JNK-IN-8 | LOXIMVI | 0.0082 | uM | 24 | hr | | Ki-67 | 2963.80 | p-Rb(S807/S811) | 214.47 | p-cJun(S73) | 101.55 | 1 | LOXIMVI-signal3 | D9 | |
| Vemurafenib | LOXIMVI | 0.0033 | uM | 24 | hr | | Ki-67 | 2960.60 | p-Rb(S807/S811) | 197.88 | p-cJun(S73) | 114.95 | 2 | LOXIMVI-signal3 | C10 | |
| JNK-IN-8 | LOXIMVI | 0.0512 | uM | 24 | hr | | Ki-67 | 2947.60 | p-Rb(S807/S811) | 217.27 | p-cJun(S73) | 73.06 | 1 | LOXIMVI-signal3 | D7 | |
| JNK-IN-8 | LOXIMVI | 0.3200 | uM | 24 | hr | | Ki-67 | 2939.70 | p-Rb(S807/S811) | 217.05 | p-cJun(S73) | 57.83 | 1 | LOXIMVI-signal3 | D5 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0000 | uM | 24 | hr | | Ki-67 | 2934.10 | p-Rb(S807/S811) | 203.26 | p-cJun(S73) | 120.51 | 2 | LOXIMVI-signal3 | G11 |
| Vemurafenib | LOXIMVI | 0.0033 | uM | 24 | hr | | Ki-67 | 2929.90 | p-Rb(S807/S811) | 202.41 | p-cJun(S73) | 113.58 | 1 | LOXIMVI-signal3 | B10 | |
| JNK-IN-8 | LOXIMVI | 0.0033 | uM | 24 | hr | | Ki-67 | 2929.10 | p-Rb(S807/S811) | 208.63 | p-cJun(S73) | 107.76 | 2 | LOXIMVI-signal3 | E10 | |
| JNK-IN-8 | LOXIMVI | 0.1280 | uM | 24 | hr | | Ki-67 | 2922.80 | p-Rb(S807/S811) | 202.58 | p-cJun(S73) | 68.33 | 1 | LOXIMVI-signal3 | D6 | |
| Vemurafenib | LOXIMVI | 0.0082 | uM | 24 | hr | | Ki-67 | 2905.80 | p-Rb(S807/S811) | 198.95 | p-cJun(S73) | 109.56 | 1 | LOXIMVI-signal3 | B9 | |
| JNK-IN-8 | LOXIMVI | 0.1280 | uM | 24 | hr | | Ki-67 | 2886.70 | p-Rb(S807/S811) | 203.46 | p-cJun(S73) | 63.66 | 2 | LOXIMVI-signal3 | E6 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0033 | uM | 24 | hr | | Ki-67 | 2882.90 | p-Rb(S807/S811) | 203.40 | p-cJun(S73) | 97.65 | 1 | LOXIMVI-signal3 | F10 |