Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20219)
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| Small Molecule | Cell Line | 2nd Drug | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Image | Measured Protein (Alexa Fluor 488) | Measured Protein Value (488) | Measured Protein (Alexa Fluor 568) | Measured Protein Value (568) | Measured Protein (Alexa Fluor 647) | Measured Protein Value (647) | Replicate | Plate Name | Plate Well |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | COLO 858 | 0.8000 | uM | 24 | hr | | Ki-67 | 680.51 | p-Rb(S807/S811) | 40.34 | p-cJun(S73) | 71.07 | 2 | Colo858-signal3 | C4 | |
| JNK-IN-8 | COLO 858 | 5.0000 | uM | 24 | hr | | Ki-67 | 2447.10 | p-Rb(S807/S811) | 231.66 | p-cJun(S73) | 37.00 | 1 | Colo858-signal3 | D2 | |
| Vemurafenib | COLO 858 | 0.1280 | uM | 24 | hr | | Ki-67 | 972.60 | p-Rb(S807/S811) | 76.98 | p-cJun(S73) | 64.88 | 1 | Colo858-signal3 | B6 | |
| Vemurafenib | COLO 858 | 2.0000 | uM | 24 | hr | | Ki-67 | 782.90 | p-Rb(S807/S811) | 45.43 | p-cJun(S73) | 59.46 | 2 | Colo858-signal3 | C3 | |
| Vemurafenib | COLO 858 | 0.0205 | uM | 24 | hr | | Ki-67 | 2138.80 | p-Rb(S807/S811) | 144.45 | p-cJun(S73) | 30.43 | 2 | Colo858-signal3 | C8 | |
| JNK-IN-8 | COLO 858 | 0.0000 | uM | 24 | hr | | Ki-67 | 2186.70 | p-Rb(S807/S811) | 147.06 | p-cJun(S73) | 28.84 | 1 | Colo858-signal3 | D11 | |
| Vemurafenib | COLO 858 | 5.0000 | uM | 24 | hr | | Ki-67 | 801.46 | p-Rb(S807/S811) | 44.01 | p-cJun(S73) | 45.24 | 1 | Colo858-signal3 | B2 | |
| Vemurafenib | COLO 858 | 0.3200 | uM | 24 | hr | | Ki-67 | 708.08 | p-Rb(S807/S811) | 48.09 | p-cJun(S73) | 72.08 | 1 | Colo858-signal3 | B5 | |
| Vemurafenib | COLO 858 | 0.0082 | uM | 24 | hr | | Ki-67 | 2239.40 | p-Rb(S807/S811) | 151.71 | p-cJun(S73) | 29.36 | 1 | Colo858-signal3 | B9 | |
| Vemurafenib | COLO 858 | 5.0000 | uM | 24 | hr | | Ki-67 | 947.93 | p-Rb(S807/S811) | 51.31 | p-cJun(S73) | 41.01 | 2 | Colo858-signal3 | C2 | |
| Vemurafenib | COLO 858 | 0.1280 | uM | 24 | hr | | Ki-67 | 1050.90 | p-Rb(S807/S811) | 82.58 | p-cJun(S73) | 62.66 | 2 | Colo858-signal3 | C6 | |
| Vemurafenib | COLO 858 | 0.0512 | uM | 24 | hr | | Ki-67 | 1637.20 | p-Rb(S807/S811) | 124.19 | p-cJun(S73) | 36.36 | 2 | Colo858-signal3 | C7 | |
| Vemurafenib | COLO 858 | 0.0082 | uM | 24 | hr | | Ki-67 | 2183.20 | p-Rb(S807/S811) | 146.71 | p-cJun(S73) | 28.18 | 2 | Colo858-signal3 | C9 | |
| JNK-IN-8 | COLO 858 | 0.0033 | uM | 24 | hr | | Ki-67 | 2257.20 | p-Rb(S807/S811) | 149.91 | p-cJun(S73) | 29.66 | 1 | Colo858-signal3 | D10 | |
| Vemurafenib | COLO 858 | 0.0033 | uM | 24 | hr | | Ki-67 | 2154.80 | p-Rb(S807/S811) | 145.55 | p-cJun(S73) | 28.64 | 1 | Colo858-signal3 | B10 | |
| Vemurafenib | COLO 858 | 0.0000 | uM | 24 | hr | | Ki-67 | 2209.00 | p-Rb(S807/S811) | 151.07 | p-cJun(S73) | 28.62 | 1 | Colo858-signal3 | B11 | |
| Vemurafenib | COLO 858 | 2.0000 | uM | 24 | hr | | Ki-67 | 772.11 | p-Rb(S807/S811) | 44.73 | p-cJun(S73) | 66.84 | 1 | Colo858-signal3 | B3 | |
| Vemurafenib | COLO 858 | 0.8000 | uM | 24 | hr | | Ki-67 | 678.24 | p-Rb(S807/S811) | 45.98 | p-cJun(S73) | 72.90 | 1 | Colo858-signal3 | B4 | |
| Vemurafenib | COLO 858 | 0.0512 | uM | 24 | hr | | Ki-67 | 1742.30 | p-Rb(S807/S811) | 126.75 | p-cJun(S73) | 38.16 | 1 | Colo858-signal3 | B7 | |
| Vemurafenib | COLO 858 | 0.0205 | uM | 24 | hr | | Ki-67 | 2103.40 | p-Rb(S807/S811) | 149.11 | p-cJun(S73) | 30.17 | 1 | Colo858-signal3 | B8 | |
| Vemurafenib | COLO 858 | 0.0033 | uM | 24 | hr | | Ki-67 | 2240.50 | p-Rb(S807/S811) | 144.95 | p-cJun(S73) | 28.17 | 2 | Colo858-signal3 | C10 | |
| Vemurafenib | COLO 858 | 0.0000 | uM | 24 | hr | | Ki-67 | 2259.80 | p-Rb(S807/S811) | 154.64 | p-cJun(S73) | 29.83 | 2 | Colo858-signal3 | C11 | |
| Vemurafenib | COLO 858 | 0.3200 | uM | 24 | hr | | Ki-67 | 660.32 | p-Rb(S807/S811) | 48.67 | p-cJun(S73) | 67.95 | 2 | Colo858-signal3 | C5 | |
| JNK-IN-8 | COLO 858 | 0.8000 | uM | 24 | hr | | Ki-67 | 2383.20 | p-Rb(S807/S811) | 179.73 | p-cJun(S73) | 31.88 | 1 | Colo858-signal3 | D4 | |
| JNK-IN-8 | COLO 858 | 2.0000 | uM | 24 | hr | | Ki-67 | 2559.90 | p-Rb(S807/S811) | 217.09 | p-cJun(S73) | 34.91 | 1 | Colo858-signal3 | D3 |