Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20219)
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| Small Molecule | Cell Line | 2nd Drug | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Image | Measured Protein (Alexa Fluor 488) | Measured Protein Value (488) | Measured Protein (Alexa Fluor 568) | Measured Protein Value (568) | Measured Protein (Alexa Fluor 647) | Measured Protein Value (647) | Replicate | Plate Name | Plate Well |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| JNK-IN-8 | LOXIMVI | 0.3200 | uM | 24 | hr | | Ki-67 | 2939.70 | p-Rb(S807/S811) | 217.05 | p-cJun(S73) | 57.83 | 1 | LOXIMVI-signal3 | D5 | |
| JNK-IN-8 | LOXIMVI | 0.1280 | uM | 24 | hr | | Ki-67 | 2922.80 | p-Rb(S807/S811) | 202.58 | p-cJun(S73) | 68.33 | 1 | LOXIMVI-signal3 | D6 | |
| JNK-IN-8 | LOXIMVI | 0.0512 | uM | 24 | hr | | Ki-67 | 2947.60 | p-Rb(S807/S811) | 217.27 | p-cJun(S73) | 73.06 | 1 | LOXIMVI-signal3 | D7 | |
| JNK-IN-8 | LOXIMVI | 0.0205 | uM | 24 | hr | | Ki-67 | 3052.30 | p-Rb(S807/S811) | 224.01 | p-cJun(S73) | 90.47 | 1 | LOXIMVI-signal3 | D8 | |
| JNK-IN-8 | LOXIMVI | 0.0082 | uM | 24 | hr | | Ki-67 | 2963.80 | p-Rb(S807/S811) | 214.47 | p-cJun(S73) | 101.55 | 1 | LOXIMVI-signal3 | D9 | |
| JNK-IN-8 | LOXIMVI | 0.0033 | uM | 24 | hr | | Ki-67 | 2929.10 | p-Rb(S807/S811) | 208.63 | p-cJun(S73) | 107.76 | 2 | LOXIMVI-signal3 | E10 | |
| JNK-IN-8 | LOXIMVI | 0.0000 | uM | 24 | hr | | Ki-67 | 3030.30 | p-Rb(S807/S811) | 205.20 | p-cJun(S73) | 122.59 | 2 | LOXIMVI-signal3 | E11 | |
| JNK-IN-8 | LOXIMVI | 5.0000 | uM | 24 | hr | | Ki-67 | 2973.70 | p-Rb(S807/S811) | 240.23 | p-cJun(S73) | 48.04 | 2 | LOXIMVI-signal3 | E2 | |
| JNK-IN-8 | LOXIMVI | 2.0000 | uM | 24 | hr | | Ki-67 | 3091.80 | p-Rb(S807/S811) | 251.41 | p-cJun(S73) | 53.20 | 2 | LOXIMVI-signal3 | E3 | |
| JNK-IN-8 | LOXIMVI | 0.8000 | uM | 24 | hr | | Ki-67 | 3017.80 | p-Rb(S807/S811) | 223.34 | p-cJun(S73) | 56.18 | 2 | LOXIMVI-signal3 | E4 | |
| JNK-IN-8 | LOXIMVI | 0.3200 | uM | 24 | hr | | Ki-67 | 2848.50 | p-Rb(S807/S811) | 207.66 | p-cJun(S73) | 57.32 | 2 | LOXIMVI-signal3 | E5 | |
| JNK-IN-8 | LOXIMVI | 0.1280 | uM | 24 | hr | | Ki-67 | 2886.70 | p-Rb(S807/S811) | 203.46 | p-cJun(S73) | 63.66 | 2 | LOXIMVI-signal3 | E6 | |
| JNK-IN-8 | LOXIMVI | 0.0512 | uM | 24 | hr | | Ki-67 | 2817.60 | p-Rb(S807/S811) | 205.31 | p-cJun(S73) | 68.42 | 2 | LOXIMVI-signal3 | E7 | |
| JNK-IN-8 | LOXIMVI | 0.0205 | uM | 24 | hr | | Ki-67 | 2981.20 | p-Rb(S807/S811) | 212.09 | p-cJun(S73) | 82.93 | 2 | LOXIMVI-signal3 | E8 | |
| JNK-IN-8 | LOXIMVI | 0.0082 | uM | 24 | hr | | Ki-67 | 2876.00 | p-Rb(S807/S811) | 199.31 | p-cJun(S73) | 94.47 | 2 | LOXIMVI-signal3 | E9 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0033 | uM | 24 | hr | | Ki-67 | 2882.90 | p-Rb(S807/S811) | 203.40 | p-cJun(S73) | 97.65 | 1 | LOXIMVI-signal3 | F10 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0000 | uM | 24 | hr | | Ki-67 | 3032.30 | p-Rb(S807/S811) | 209.50 | p-cJun(S73) | 127.94 | 1 | LOXIMVI-signal3 | F11 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 5.0000 | uM | 24 | hr | | Ki-67 | 2814.00 | p-Rb(S807/S811) | 96.96 | p-cJun(S73) | 30.63 | 1 | LOXIMVI-signal3 | F2 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 2.0000 | uM | 24 | hr | | Ki-67 | 2379.60 | p-Rb(S807/S811) | 93.92 | p-cJun(S73) | 26.61 | 1 | LOXIMVI-signal3 | F3 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.8000 | uM | 24 | hr | | Ki-67 | 2249.30 | p-Rb(S807/S811) | 93.65 | p-cJun(S73) | 24.47 | 1 | LOXIMVI-signal3 | F4 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.3200 | uM | 24 | hr | | Ki-67 | 2320.10 | p-Rb(S807/S811) | 113.12 | p-cJun(S73) | 29.40 | 1 | LOXIMVI-signal3 | F5 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.1280 | uM | 24 | hr | | Ki-67 | 2553.90 | p-Rb(S807/S811) | 157.20 | p-cJun(S73) | 41.82 | 1 | LOXIMVI-signal3 | F6 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0512 | uM | 24 | hr | | Ki-67 | 2628.70 | p-Rb(S807/S811) | 180.11 | p-cJun(S73) | 54.15 | 1 | LOXIMVI-signal3 | F7 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0205 | uM | 24 | hr | | Ki-67 | 2734.80 | p-Rb(S807/S811) | 188.75 | p-cJun(S73) | 65.47 | 1 | LOXIMVI-signal3 | F8 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0082 | uM | 24 | hr | | Ki-67 | 2742.00 | p-Rb(S807/S811) | 188.71 | p-cJun(S73) | 92.00 | 1 | LOXIMVI-signal3 | F9 |