Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | WM-115 | 1.0000 | uM | 24 | hr | 648 | 60 | 1.1230 | 1.1516 | 0.0926 | 0.0874 | 4 |
| SB590885 | WM-115 | 1.0000 | uM | 48 | hr | 598 | 51 | 1.1043 | 0.9721 | 0.0853 | 0.1007 | 1 |
| SB590885 | WM-115 | 1.0000 | uM | 48 | hr | 544 | 47 | 1.0034 | 0.9721 | 0.0864 | 0.1007 | 2 |
| SB590885 | WM-115 | 1.0000 | uM | 48 | hr | 422 | 57 | 0.7369 | 0.9721 | 0.1351 | 0.1007 | 3 |
| SB590885 | WM-115 | 1.0000 | uM | 48 | hr | 572 | 55 | 1.0438 | 0.9721 | 0.0962 | 0.1007 | 4 |
| SB590885 | WM-115 | 1.0000 | uM | 72 | hr | 1953 | 316 | 0.5400 | 0.5839 | 0.1618 | 0.1444 | 1 |
| SB590885 | WM-115 | 1.0000 | uM | 72 | hr | 1871 | 283 | 0.5238 | 0.5839 | 0.1513 | 0.1444 | 2 |
| SB590885 | WM-115 | 1.0000 | uM | 72 | hr | 2281 | 330 | 0.6436 | 0.5839 | 0.1447 | 0.1444 | 3 |
| SB590885 | WM-115 | 1.0000 | uM | 72 | hr | 2163 | 259 | 0.6281 | 0.5839 | 0.1197 | 0.1444 | 4 |
| SB590885 | WM-115 | 3.1600 | uM | 24 | hr | 723 | 92 | 1.2051 | 1.2839 | 0.1273 | 0.0958 | 1 |
| SB590885 | WM-115 | 3.1600 | uM | 24 | hr | 669 | 78 | 1.1287 | 1.2839 | 0.1166 | 0.0958 | 2 |
| SB590885 | WM-115 | 3.1600 | uM | 24 | hr | 874 | 62 | 1.5508 | 1.2839 | 0.0709 | 0.0958 | 3 |
| SB590885 | WM-115 | 3.1600 | uM | 24 | hr | 703 | 48 | 1.2510 | 1.2839 | 0.0683 | 0.0958 | 4 |
| SB590885 | WM-115 | 3.1600 | uM | 48 | hr | 507 | 59 | 0.9045 | 0.6829 | 0.1164 | 0.1306 | 1 |
| SB590885 | WM-115 | 3.1600 | uM | 48 | hr | 456 | 58 | 0.8035 | 0.6829 | 0.1272 | 0.1306 | 2 |
| SB590885 | WM-115 | 3.1600 | uM | 48 | hr | 266 | 42 | 0.4522 | 0.6829 | 0.1579 | 0.1306 | 3 |
| SB590885 | WM-115 | 3.1600 | uM | 48 | hr | 322 | 39 | 0.5713 | 0.6829 | 0.1211 | 0.1306 | 4 |
| SB590885 | WM-115 | 3.1600 | uM | 72 | hr | 1981 | 349 | 0.5383 | 0.5728 | 0.1762 | 0.1576 | 1 |
| SB590885 | WM-115 | 3.1600 | uM | 72 | hr | 1850 | 286 | 0.5159 | 0.5728 | 0.1546 | 0.1576 | 2 |
| SB590885 | WM-115 | 3.1600 | uM | 72 | hr | 2178 | 349 | 0.6033 | 0.5728 | 0.1602 | 0.1576 | 3 |
| SB590885 | WM-115 | 3.1600 | uM | 72 | hr | 2232 | 311 | 0.6337 | 0.5728 | 0.1393 | 0.1576 | 4 |
| PLX-4720 | WM-115 | 0.0032 | uM | 24 | hr | 677 | 28 | 1.2395 | 1.1430 | 0.0414 | 0.0488 | 1 |
| PLX-4720 | WM-115 | 0.0032 | uM | 24 | hr | 624 | 27 | 1.1402 | 1.1430 | 0.0433 | 0.0488 | 2 |
| PLX-4720 | WM-115 | 0.0032 | uM | 24 | hr | 533 | 27 | 0.9664 | 1.1430 | 0.0507 | 0.0488 | 3 |
| PLX-4720 | WM-115 | 0.0032 | uM | 24 | hr | 683 | 41 | 1.2261 | 1.1430 | 0.0600 | 0.0488 | 4 |