Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
PLX-4720 C32 0.1000
uM
 48
hr
 2218 242 0.9615 1.0106 0.1091 0.1052 2
PLX-4720 C32 0.1000
uM
 48
hr
 2511 244 1.1031 1.0106 0.0972 0.1052 3
PLX-4720 C32 0.1000
uM
 48
hr
 2418 159 1.0992 1.0106 0.0658 0.1052 4
PLX-4720 C32 0.1000
uM
 72
hr
 2073 69 0.8750 0.9374 0.0333 0.0354 1
PLX-4720 C32 0.1000
uM
 72
hr
 2304 100 0.9623 0.9374 0.0434 0.0354 2
PLX-4720 C32 0.1000
uM
 72
hr
 2300 79 0.9697 0.9374 0.0343 0.0354 3
PLX-4720 C32 0.1000
uM
 72
hr
 2227 68 0.9426 0.9374 0.0305 0.0354 4
PLX-4720 C32 0.3160
uM
 24
hr
 1973 326 0.9522 0.9421 0.1652 0.1737 1
PLX-4720 C32 0.3160
uM
 24
hr
 1982 341 0.9488 0.9421 0.1721 0.1737 2
PLX-4720 C32 0.3160
uM
 24
hr
 2025 391 0.9447 0.9421 0.1931 0.1737 3
PLX-4720 C32 0.3160
uM
 24
hr
 1910 314 0.9227 0.9421 0.1644 0.1737 4
PLX-4720 C32 0.3160
uM
 48
hr
 1854 281 0.7654 0.8575 0.1516 0.1431 1
PLX-4720 C32 0.3160
uM
 48
hr
 1860 308 0.7552 0.8575 0.1656 0.1431 2
PLX-4720 C32 0.3160
uM
 48
hr
 2288 288 0.9732 0.8575 0.1259 0.1431 3
PLX-4720 C32 0.3160
uM
 48
hr
 2210 286 0.9362 0.8575 0.1294 0.1431 4
PLX-4720 C32 0.3160
uM
 72
hr
 1393 337 0.4611 0.5161 0.2419 0.2146 1
PLX-4720 C32 0.3160
uM
 72
hr
 1482 315 0.5095 0.5161 0.2126 0.2146 2
PLX-4720 C32 0.3160
uM
 72
hr
 1549 345 0.5257 0.5161 0.2227 0.2146 3
PLX-4720 C32 0.3160
uM
 72
hr
 1589 288 0.5680 0.5161 0.1813 0.2146 4
PLX-4720 C32 1.0000
uM
 24
hr
 1929 469 0.8441 0.8236 0.2431 0.2452 1
PLX-4720 C32 1.0000
uM
 24
hr
 1949 537 0.8164 0.8236 0.2755 0.2452 2
PLX-4720 C32 1.0000
uM
 24
hr
 1814 427 0.8019 0.8236 0.2354 0.2452 3
PLX-4720 C32 1.0000
uM
 24
hr
 1861 422 0.8320 0.8236 0.2268 0.2452 4
PLX-4720 C32 1.0000
uM
 48
hr
 1558 719 0.4082 0.4542 0.4615 0.4653 1
PLX-4720 C32 1.0000
uM
 48
hr
 1581 885 0.3387 0.4542 0.5598 0.4653 2