Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | C32 | 0.0100 | uM | 48 | hr | 1600 | 351 | 0.6077 | 0.9050 | 0.2194 | 0.1586 | 1 |
| PLX-4720 | C32 | 0.0100 | uM | 48 | hr | 1831 | 271 | 0.7591 | 0.9050 | 0.1480 | 0.1586 | 2 |
| PLX-4720 | C32 | 0.0100 | uM | 48 | hr | 2570 | 368 | 1.0714 | 0.9050 | 0.1432 | 0.1586 | 3 |
| PLX-4720 | C32 | 0.0100 | uM | 48 | hr | 2772 | 343 | 1.1819 | 0.9050 | 0.1237 | 0.1586 | 4 |
| PLX-4720 | C32 | 0.0100 | uM | 72 | hr | 2471 | 251 | 0.9693 | 1.0850 | 0.1016 | 0.0849 | 1 |
| PLX-4720 | C32 | 0.0100 | uM | 72 | hr | 2714 | 194 | 1.1002 | 1.0850 | 0.0715 | 0.0849 | 2 |
| PLX-4720 | C32 | 0.0100 | uM | 72 | hr | 2728 | 221 | 1.0946 | 1.0850 | 0.0810 | 0.0849 | 3 |
| PLX-4720 | C32 | 0.0100 | uM | 72 | hr | 2945 | 252 | 1.1758 | 1.0850 | 0.0856 | 0.0849 | 4 |
| PLX-4720 | C32 | 0.0316 | uM | 24 | hr | 1988 | 307 | 0.9719 | 1.0403 | 0.1544 | 0.1193 | 1 |
| PLX-4720 | C32 | 0.0316 | uM | 24 | hr | 2082 | 257 | 1.0551 | 1.0403 | 0.1234 | 0.1193 | 2 |
| PLX-4720 | C32 | 0.0316 | uM | 24 | hr | 2094 | 231 | 1.0771 | 1.0403 | 0.1103 | 0.1193 | 3 |
| PLX-4720 | C32 | 0.0316 | uM | 24 | hr | 2007 | 179 | 1.0569 | 1.0403 | 0.0892 | 0.1193 | 4 |
| PLX-4720 | C32 | 0.0316 | uM | 48 | hr | 1968 | 401 | 0.7625 | 0.9286 | 0.2038 | 0.1583 | 1 |
| PLX-4720 | C32 | 0.0316 | uM | 48 | hr | 2008 | 355 | 0.8043 | 0.9286 | 0.1768 | 0.1583 | 2 |
| PLX-4720 | C32 | 0.0316 | uM | 48 | hr | 2529 | 355 | 1.0578 | 0.9286 | 0.1404 | 0.1583 | 3 |
| PLX-4720 | C32 | 0.0316 | uM | 48 | hr | 2523 | 283 | 1.0899 | 0.9286 | 0.1122 | 0.1583 | 4 |
| PLX-4720 | C32 | 0.0316 | uM | 72 | hr | 2777 | 157 | 1.1439 | 1.0994 | 0.0565 | 0.0684 | 1 |
| PLX-4720 | C32 | 0.0316 | uM | 72 | hr | 2641 | 217 | 1.0583 | 1.0994 | 0.0822 | 0.0684 | 2 |
| PLX-4720 | C32 | 0.0316 | uM | 72 | hr | 2778 | 174 | 1.1369 | 1.0994 | 0.0626 | 0.0684 | 3 |
| PLX-4720 | C32 | 0.0316 | uM | 72 | hr | 2613 | 189 | 1.0583 | 1.0994 | 0.0723 | 0.0684 | 4 |
| PLX-4720 | C32 | 0.1000 | uM | 24 | hr | 1907 | 284 | 0.9384 | 1.0076 | 0.1489 | 0.1525 | 1 |
| PLX-4720 | C32 | 0.1000 | uM | 24 | hr | 2021 | 293 | 0.9991 | 1.0076 | 0.1450 | 0.1525 | 2 |
| PLX-4720 | C32 | 0.1000 | uM | 24 | hr | 2245 | 377 | 1.0800 | 1.0076 | 0.1679 | 0.1525 | 3 |
| PLX-4720 | C32 | 0.1000 | uM | 24 | hr | 2057 | 305 | 1.0129 | 1.0076 | 0.1483 | 0.1525 | 4 |
| PLX-4720 | C32 | 0.1000 | uM | 48 | hr | 2122 | 316 | 0.8788 | 1.0106 | 0.1489 | 0.1052 | 1 |