Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | C32 | 0.0100 | uM | 24 | hr | 2002 | 267 | 1.0031 | 0.9946 | 0.1334 | 0.1387 | 3 |
| Vemurafenib | C32 | 0.0100 | uM | 24 | hr | 2117 | 236 | 1.0875 | 0.9946 | 0.1115 | 0.1387 | 4 |
| Vemurafenib | C32 | 0.0100 | uM | 48 | hr | 2050 | 364 | 0.8204 | 0.9013 | 0.1776 | 0.1730 | 1 |
| Vemurafenib | C32 | 0.0100 | uM | 48 | hr | 1745 | 350 | 0.6788 | 0.9013 | 0.2006 | 0.1730 | 2 |
| Vemurafenib | C32 | 0.0100 | uM | 48 | hr | 2712 | 412 | 1.1191 | 0.9013 | 0.1519 | 0.1730 | 3 |
| Vemurafenib | C32 | 0.0100 | uM | 48 | hr | 2420 | 392 | 0.9868 | 0.9013 | 0.1620 | 0.1730 | 4 |
| Vemurafenib | C32 | 0.0100 | uM | 72 | hr | 2574 | 221 | 1.0273 | 1.0714 | 0.0859 | 0.0907 | 1 |
| Vemurafenib | C32 | 0.0100 | uM | 72 | hr | 2619 | 251 | 1.0339 | 1.0714 | 0.0958 | 0.0907 | 2 |
| Vemurafenib | C32 | 0.0100 | uM | 72 | hr | 2977 | 259 | 1.1867 | 1.0714 | 0.0870 | 0.0907 | 3 |
| Vemurafenib | C32 | 0.0100 | uM | 72 | hr | 2624 | 247 | 1.0378 | 1.0714 | 0.0941 | 0.0907 | 4 |
| Vemurafenib | C32 | 0.0316 | uM | 24 | hr | 2050 | 377 | 0.9673 | 1.0274 | 0.1839 | 0.1658 | 1 |
| Vemurafenib | C32 | 0.0316 | uM | 24 | hr | 2159 | 412 | 1.0100 | 1.0274 | 0.1908 | 0.1658 | 2 |
| Vemurafenib | C32 | 0.0316 | uM | 24 | hr | 2182 | 333 | 1.0690 | 1.0274 | 0.1526 | 0.1658 | 3 |
| Vemurafenib | C32 | 0.0316 | uM | 24 | hr | 2128 | 289 | 1.0632 | 1.0274 | 0.1358 | 0.1658 | 4 |
| Vemurafenib | C32 | 0.0316 | uM | 48 | hr | 1898 | 404 | 0.7269 | 0.8907 | 0.2129 | 0.1860 | 1 |
| Vemurafenib | C32 | 0.0316 | uM | 48 | hr | 1917 | 427 | 0.7250 | 0.8907 | 0.2227 | 0.1860 | 2 |
| Vemurafenib | C32 | 0.0316 | uM | 48 | hr | 2658 | 367 | 1.1147 | 0.8907 | 0.1381 | 0.1860 | 3 |
| Vemurafenib | C32 | 0.0316 | uM | 48 | hr | 2467 | 420 | 0.9960 | 0.8907 | 0.1703 | 0.1860 | 4 |
| Vemurafenib | C32 | 0.0316 | uM | 72 | hr | 2494 | 196 | 1.0033 | 1.0243 | 0.0786 | 0.0843 | 1 |
| Vemurafenib | C32 | 0.0316 | uM | 72 | hr | 2593 | 219 | 1.0365 | 1.0243 | 0.0845 | 0.0843 | 2 |
| Vemurafenib | C32 | 0.0316 | uM | 72 | hr | 2505 | 243 | 0.9876 | 1.0243 | 0.0970 | 0.0843 | 3 |
| Vemurafenib | C32 | 0.0316 | uM | 72 | hr | 2655 | 205 | 1.0697 | 1.0243 | 0.0772 | 0.0843 | 4 |
| Vemurafenib | C32 | 0.1000 | uM | 24 | hr | 2065 | 385 | 0.9713 | 0.9852 | 0.1864 | 0.1861 | 1 |
| Vemurafenib | C32 | 0.1000 | uM | 24 | hr | 1958 | 351 | 0.9291 | 0.9852 | 0.1793 | 0.1861 | 2 |
| Vemurafenib | C32 | 0.1000 | uM | 24 | hr | 2154 | 414 | 1.0060 | 0.9852 | 0.1922 | 0.1861 | 3 |