Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Vemurafenib C32 0.1000
uM
 24
hr
 2199 410 1.0343 0.9852 0.1865 0.1861 4
Vemurafenib C32 0.1000
uM
 48
hr
 2057 297 0.8564 0.9598 0.1444 0.1267 1
Vemurafenib C32 0.1000
uM
 48
hr
 2070 306 0.8583 0.9598 0.1478 0.1267 2
Vemurafenib C32 0.1000
uM
 48
hr
 2542 245 1.1177 0.9598 0.0964 0.1267 3
Vemurafenib C32 0.1000
uM
 48
hr
 2346 277 1.0067 0.9598 0.1181 0.1267 4
Vemurafenib C32 0.1000
uM
 72
hr
 2100 145 0.8536 0.8750 0.0690 0.0610 1
Vemurafenib C32 0.1000
uM
 72
hr
 1979 143 0.8016 0.8750 0.0723 0.0610 2
Vemurafenib C32 0.1000
uM
 72
hr
 2129 105 0.8837 0.8750 0.0493 0.0610 3
Vemurafenib C32 0.1000
uM
 72
hr
 2325 124 0.9610 0.8750 0.0533 0.0610 4
Vemurafenib C32 0.3160
uM
 24
hr
 2265 483 1.0303 0.9968 0.2133 0.2018 1
Vemurafenib C32 0.3160
uM
 24
hr
 2156 410 1.0095 0.9968 0.1902 0.2018 2
Vemurafenib C32 0.3160
uM
 24
hr
 2257 441 1.0499 0.9968 0.1954 0.2018 3
Vemurafenib C32 0.3160
uM
 24
hr
 1961 409 0.8973 0.9968 0.2086 0.2018 4
Vemurafenib C32 0.3160
uM
 48
hr
 2117 222 0.9221 0.9875 0.1049 0.0971 1
Vemurafenib C32 0.3160
uM
 48
hr
 2020 239 0.8666 0.9875 0.1183 0.0971 2
Vemurafenib C32 0.3160
uM
 48
hr
 2518 185 1.1352 0.9875 0.0735 0.0971 3
Vemurafenib C32 0.3160
uM
 48
hr
 2322 213 1.0262 0.9875 0.0917 0.0971 4
Vemurafenib C32 0.3160
uM
 72
hr
 1638 173 0.6396 0.6837 0.1056 0.1145 1
Vemurafenib C32 0.3160
uM
 72
hr
 1716 233 0.6475 0.6837 0.1358 0.1145 2
Vemurafenib C32 0.3160
uM
 72
hr
 1910 200 0.7466 0.6837 0.1047 0.1145 3
Vemurafenib C32 0.3160
uM
 72
hr
 1808 202 0.7012 0.6837 0.1117 0.1145 4
Vemurafenib C32 1.0000
uM
 24
hr
 2013 331 0.9725 0.9267 0.1644 0.1700 1
Vemurafenib C32 1.0000
uM
 24
hr
 2097 381 0.9921 0.9267 0.1817 0.1700 2
Vemurafenib C32 1.0000
uM
 24
hr
 1995 328 0.9638 0.9267 0.1644 0.1700 3
Vemurafenib C32 1.0000
uM
 24
hr
 1621 275 0.7782 0.9267 0.1697 0.1700 4