Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | COLO 858 | 0.0100 | uM | 24 | hr | 4571 | 215 | 1.4551 | 1.1523 | 0.0470 | 0.0452 | 1 |
| PLX-4720 | COLO 858 | 0.0100 | uM | 24 | hr | 4528 | 204 | 1.4444 | 1.1523 | 0.0451 | 0.0452 | 2 |
| PLX-4720 | COLO 858 | 0.0100 | uM | 24 | hr | 2649 | 127 | 0.8424 | 1.1523 | 0.0479 | 0.0452 | 3 |
| PLX-4720 | COLO 858 | 0.0100 | uM | 24 | hr | 2707 | 110 | 0.8675 | 1.1523 | 0.0406 | 0.0452 | 4 |
| PLX-4720 | COLO 858 | 0.0100 | uM | 48 | hr | 4938 | 251 | 1.0709 | 1.0692 | 0.0508 | 0.0523 | 1 |
| PLX-4720 | COLO 858 | 0.0100 | uM | 48 | hr | 4507 | 243 | 0.9743 | 1.0692 | 0.0539 | 0.0523 | 2 |
| PLX-4720 | COLO 858 | 0.0100 | uM | 48 | hr | 4998 | 272 | 1.0798 | 1.0692 | 0.0544 | 0.0523 | 3 |
| PLX-4720 | COLO 858 | 0.0100 | uM | 48 | hr | 5307 | 266 | 1.1518 | 1.0692 | 0.0501 | 0.0523 | 4 |
| PLX-4720 | COLO 858 | 0.0100 | uM | 72 | hr | 3856 | 306 | 1.2895 | 1.2018 | 0.0794 | 0.0826 | 1 |
| PLX-4720 | COLO 858 | 0.0100 | uM | 72 | hr | 3779 | 306 | 1.2615 | 1.2018 | 0.0810 | 0.0826 | 2 |
| PLX-4720 | COLO 858 | 0.0100 | uM | 72 | hr | 3187 | 255 | 1.0650 | 1.2018 | 0.0800 | 0.0826 | 3 |
| PLX-4720 | COLO 858 | 0.0100 | uM | 72 | hr | 3603 | 324 | 1.1910 | 1.2018 | 0.0899 | 0.0826 | 4 |
| PLX-4720 | COLO 858 | 0.0316 | uM | 24 | hr | 4818 | 188 | 1.5466 | 1.2060 | 0.0390 | 0.0424 | 1 |
| PLX-4720 | COLO 858 | 0.0316 | uM | 24 | hr | 4424 | 191 | 1.4140 | 1.2060 | 0.0432 | 0.0424 | 2 |
| PLX-4720 | COLO 858 | 0.0316 | uM | 24 | hr | 2923 | 116 | 0.9376 | 1.2060 | 0.0397 | 0.0424 | 3 |
| PLX-4720 | COLO 858 | 0.0316 | uM | 24 | hr | 2911 | 139 | 0.9260 | 1.2060 | 0.0478 | 0.0424 | 4 |
| PLX-4720 | COLO 858 | 0.0316 | uM | 48 | hr | 4742 | 209 | 1.0357 | 1.0601 | 0.0441 | 0.0462 | 1 |
| PLX-4720 | COLO 858 | 0.0316 | uM | 48 | hr | 4587 | 206 | 1.0010 | 1.0601 | 0.0449 | 0.0462 | 2 |
| PLX-4720 | COLO 858 | 0.0316 | uM | 48 | hr | 4910 | 214 | 1.0730 | 1.0601 | 0.0436 | 0.0462 | 3 |
| PLX-4720 | COLO 858 | 0.0316 | uM | 48 | hr | 5221 | 272 | 1.1308 | 1.0601 | 0.0521 | 0.0462 | 4 |
| PLX-4720 | COLO 858 | 0.0316 | uM | 72 | hr | 3431 | 239 | 1.1594 | 1.1877 | 0.0697 | 0.0717 | 1 |
| PLX-4720 | COLO 858 | 0.0316 | uM | 72 | hr | 3302 | 252 | 1.1079 | 1.1877 | 0.0763 | 0.0717 | 2 |
| PLX-4720 | COLO 858 | 0.0316 | uM | 72 | hr | 3807 | 235 | 1.2975 | 1.1877 | 0.0617 | 0.0717 | 3 |
| PLX-4720 | COLO 858 | 0.0316 | uM | 72 | hr | 3546 | 281 | 1.1860 | 1.1877 | 0.0792 | 0.0717 | 4 |
| PLX-4720 | COLO 858 | 0.1000 | uM | 24 | hr | 4707 | 250 | 1.4888 | 1.1715 | 0.0531 | 0.0482 | 1 |