Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | MWCL.1 | PIP4K2A | AKELPTLKDNDFINEGQK | ATP | -7.441070191 | 1 | uM |
| Ibrutinib | MWCL.1 | PI42C | TLVIKEVSSEDIADMHSNLSNYHQYIVK | ATP | -11.91082052 | 1 | uM |
| Ibrutinib | MWCL.1 | FYV1 | GGKSGAAFYATEDDRFILK | ATP | 11.14234301 | 1 | uM |
| Ibrutinib | MWCL.1 | PITSLRE | DLKTSNLLLSHAGILK | Lys2 | 3.557382001 | 1 | uM |
| Ibrutinib | MWCL.1 | PKD2 | DVAVKVIDK | Lys1 | 2.246069667 | 1 | uM |
| Ibrutinib | MWCL.1 | PKD3 | DVAIKVIDK | Lys1 | -13.34959871 | 1 | uM |
| Ibrutinib | MWCL.1 | PKN1 | VLLSEFRPSGELFAIKALK | Lys1 | 16.99256727 | 1 | uM |
| Ibrutinib | MWCL.1 | PKR | DLKPSNIFLVDTK | Lys2 | -2.353428662 | 1 | uM |
| Ibrutinib | MWCL.1 | PLK1 | CFEISDADTKEVFAGKIVPK | Lys1 | 17.91776398 | 1 | uM |
| Ibrutinib | MWCL.1 | PRP4 | CNILHADIKPDNILVNESK | Lys2 | -47.19430914 | 1 | uM |
| Ibrutinib | MWCL.1 | PRPK | FLSGLELVKQGAEAR | ATP Loop | 0.793300257 | 1 | uM |
| Ibrutinib | MWCL.1 | FAK2 | YIEDEDYYKASVTR | Activation Loop | -32.32583925 | 1 | uM |
| Ibrutinib | MWCL.1 | RAF1 | DMKSNNIFLHEGLTVK | Lys2 | 14.46269151 | 1 | uM |
| Ibrutinib | MWCL.1 | RIPK2 | VQVAVKHLHIHTPLLDSER | Lys1 | > 68 | 1 | uM |
| Ibrutinib | MWCL.1 | RIPK3 | DLKPSNVLLDPELHVK | Lys2 | 34.80243024 | 1 | uM |
| Ibrutinib | MWCL.1 | ROCK1,ROCK2 | DVKPDNMLLDK | Lys2 | -26.49370805 | 1 | uM |
| Ibrutinib | MWCL.1 | RSK1 domain1 | DLKPENILLDEEGHIKLTDFGLSKEAIDHEK | Lys2 | 2.54789347 | 1 | uM |
| Ibrutinib | MWCL.1 | RSK1_domain2 | DLKPSNILYVDESGNPECLR | Lys2 | 1.877907886 | 1 | uM |
| Ibrutinib | MWCL.1 | RSK1,RSK2,RSK3_domain1 | DLKPENILLDEEGHIK | Lys2 | -1.802016002 | 1 | uM |
| Ibrutinib | MWCL.1 | RSK2_domain2 | DLKPSNILYVDESGNPESIR | Lys2 | -1.494987262 | 1 | uM |
| Ibrutinib | MWCL.1 | RSK3_domain1 | DLKPENILLDEEGHIKITDFGLSK | Lys2 | 14.0178726 | 1 | uM |
| Ibrutinib | MWCL.1 | RSK4 domain1 | DLKPENILLDEIGHIK | Lys2 | ND | 1 | uM |
| Ibrutinib | MWCL.1 | RSKL1_domain1 | VLGVIDKVLLVMDTR | ATP | -15.12901365 | 1 | uM |
| Ibrutinib | MWCL.1 | SGK3 | FYAVKVLQK | Lys1 | 17.32140463 | 1 | uM |
| Ibrutinib | MWCL.1 | SLK | DLKAGNILFTLDGDIK | Lys2 | -9.023971917 | 1 | uM |