Ibrutinib KiNativ -- single dose experiment - Dataset (ID:20214)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| Ibrutinib | MWCL.1 | SMG1 | DTVTIHSVGGTITILPTKTKPK | ATP | 0.095784852 | 1 | uM |
| Ibrutinib | MWCL.1 | SNRK | DLKPENVVFFEK | Lys2 | 37.42537525 | 1 | uM |
| Ibrutinib | MWCL.1 | SRPK1 | IIHTDIKPENILLSVNEQYIR | Lys2 | 6.391610653 | 1 | uM |
| Ibrutinib | MWCL.1 | SRPK1/2 | FVAMKVVK | Lys1 | -15.86963189 | 1 | uM |
| Ibrutinib | MWCL.1 | STLK5 | YSVKVLPWLSPEVLQQNLQGYDAK | Activation Loop | -1.817329189 | 1 | uM |
| Ibrutinib | MWCL.1 | STLK6 | HTPTGTLVTIKITNLENCNEER | Lys1 | -14.23123739 | 1 | uM |
| Ibrutinib | MWCL.1 | SYK | ISDFGLSKALR | Activation Loop | 5.294162573 | 1 | uM |
| Ibrutinib | MWCL.1 | MAP3K7,TAK1 | DLKPPNLLLVAGGTVLK | Lys2 | 21.92723112 | 1 | uM |
| Ibrutinib | MWCL.1 | TAO1,TAOK3 | DIKAGNILLTEPGQVK | Lys2 | -6.125215797 | 1 | uM |
| Ibrutinib | MWCL.1 | TAOK2 | DVKAGNILLSEPGLVK | Lys2 | -2.20314635 | 1 | uM |
| Ibrutinib | MWCL.1 | TBK1 | TGDLFAIKVFNNISFLRPVDVQMR | Lys1 | -4.532128705 | 1 | uM |
| Ibrutinib | MWCL.1 | TEC | YVLDDQYTSSSGAKFPVK | Activation Loop | > 95 | 1 | uM |
| Ibrutinib | MWCL.1 | TLK1 | YLNEIKPPIIHYDLKPGNILLVDGTACGEIK | Lys2 | 4.10725124 | 1 | uM |
| Ibrutinib | MWCL.1 | TLK1/2 | YLNEIKPPIIHYDLKPGNILLVNGTACGEIK | Lys2 | 6.438215368 | 1 | uM |
| Ibrutinib | MWCL.1 | ULK1 | DLKPQNILLSNPAGR | Lys2 | -3.373570817 | 1 | uM |
| Ibrutinib | MWCL.1 | ULK3 | NISHLDLKPQNILLSSLEKPHLK | Lys2 | -18.27216024 | 1 | uM |
| Ibrutinib | MWCL.1 | VRK2 | MLDVLEYIHENEYVHGDIKAANLLLGYK | Lys2 | -8.993081564 | 1 | uM |
| Ibrutinib | MWCL.1 | WEE1 | YIHSMSLVHMDIKPSNIFISR | Lys2 | -33.51822992 | 1 | uM |
| Ibrutinib | MWCL.1 | Wnk1,Wnk2,Wnk3 | DLKCDNIFITGPTGSVK | Lys2 | -21.21985149 | 1 | uM |
| Ibrutinib | MWCL.1 | ZC1/HGK,ZC2/TNIK,ZC3/MINK | DIKGQNVLLTENAEVK | Lys2 | -2.178793166 | 1 | uM |
| Ibrutinib | MWCL.1 | ZC2/TNIK | TGQLAAIKVMDVTGDEEEEIKQEINMLKK | Lys1 | -11.51803213 | 1 | uM |
| Ibrutinib | BCWM.1 | ABL,ARG | LMTGDTYTAHAGAKFPIK | Activation Loop | 0.604314574 | 1 | uM |
| Ibrutinib | BCWM.1 | ABL,ARG | YSLTVAVKTLKEDTMEVEEFLK | Lys1 | -47.25685345 | 1 | uM |
| Ibrutinib | BCWM.1 | ACK | TVSVAVKCLKPDVLSQPEAMDDFIR | Lys1 | -31.80246763 | 1 | uM |
| Ibrutinib | BCWM.1 | AMPKa1,AMPKa2 | DLKPENVLLDAHMNAK | Lys2 | -38.52805558 | 1 | uM |