JNK-IN-8 KiNativ -- single dose experiment - Dataset (ID:20213)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| JNK-IN-8 | A-375 | ABL,ARG | LMTGDTYTAHAGAkFPIK | Activation Loop | -6.9 | 1 | uM |
| JNK-IN-8 | A-375 | ABL,ARG | YSLTVAVkTLKEDTMEVEEFLK | Lys1 | -2.7 | 1 | uM |
| JNK-IN-8 | A-375 | ACK | TVSVAVKCLkPDVLSQPEAMDDFIR | Lys1 | -14.1 | 1 | uM |
| JNK-IN-8 | A-375 | AKT1 | GTFGkVILVK | ATP Loop | -8.0 | 1 | uM |
| JNK-IN-8 | A-375 | AKT2,AKT3 | GTFGkVILVR | ATP Loop | -23.6 | 1 | uM |
| JNK-IN-8 | A-375 | AMPKa1 | IGHYILGDTLGVGTFGkVK | ATP Loop | -15.4 | 1 | uM |
| JNK-IN-8 | A-375 | AMPKa1,AMPKa2 | VAVkILNR | Lys1 | -7.8 | 1 | uM |
| JNK-IN-8 | A-375 | AMPKa1,AMPKa2 | DLkPENVLLDAHMNAK | Lys2 | -31.1 | 1 | uM |
| JNK-IN-8 | A-375 | ARAF | DLkSNNIFLHEGLTVK | Lys2 | -49.1 | 1 | uM |
| JNK-IN-8 | A-375 | ATM | QLVkGRDDLRQDAVMQQVFQMCNTLLQR | ATP | 10.6 | 1 | uM |
| JNK-IN-8 | A-375 | ATR | FYIMMCkPK | ATP | -21.9 | 1 | uM |
| JNK-IN-8 | A-375 | ATR | kAGHHQTAYNALLNAGESR | Protein Kinase Domain | 7.5 | 1 | uM |
| JNK-IN-8 | A-375 | AurA | DIkPENLLLGSAGELK | Lys2 | -8.0 | 1 | uM |
| JNK-IN-8 | A-375 | AurA,AurB,AurC | GkFGNVYLAR | ATP Loop | -11.3 | 1 | uM |
| JNK-IN-8 | A-375 | AXL | NCMLNENMSVCVADFGLSkK | Activation Loop | -28.7 | 1 | uM |
| JNK-IN-8 | A-375 | BRAF | DLkSNNIFLHEDLTVK | Lys2 | -23.7 | 1 | uM |
| JNK-IN-8 | A-375 | CaMK1a | LVAIkCIAK | Lys1 | -33.0 | 1 | uM |
| JNK-IN-8 | A-375 | CaMK2g | TSTQEYAAkIINTK | Lys1 | -16.7 | 1 | uM |
| JNK-IN-8 | A-375 | CaMK2g | KTSTQEYAAkIINTKK | Lys1 | -8.4 | 1 | uM |
| JNK-IN-8 | A-375 | CaMKK2 | LAYNENDNTYYAMkVLSK | Lys1 | -26.9 | 1 | uM |
| JNK-IN-8 | A-375 | CASK | ETGQQFAVkIVDVAK | Lys1 | 5.1 | 1 | uM |
| JNK-IN-8 | A-375 | CDC2 | VLHRDLkPQNLLIDDKGTIK | Lys2 | 2.2 | 1 | uM |
| JNK-IN-8 | A-375 | CDC2 | DLkPQNLLIDDKGTIK | Lys2 | -14.9 | 1 | uM |
| JNK-IN-8 | A-375 | CDK10 | DLkVSNLLMTDK | Lys2 | 8.3 | 1 | uM |
| JNK-IN-8 | A-375 | CDK11,CDK8 | DLkPANILVMGEGPER | Lys2 | 0.4 | 1 | uM |