JNK-IN-8 KiNativ -- single dose experiment - Dataset (ID:20213)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| JNK-IN-8 | A-375 | Wnk1,Wnk2,Wnk4 | IGDLGLATLkR | Activation Loop | -15.1 | 1 | uM |
| JNK-IN-8 | A-375 | MAP2K6 | MCDFGISGYLVDSVAkTIDAGCKPYMAPER | Activation Loop | -8.9 | 1 | uM |
| JNK-IN-8 | A-375 | RSK2_domain1 | LTDFGLSkESIDHEKK | Activation Loop | -47.2 | 1 | uM |
| JNK-IN-8 | A-375 | TYK2(Kin.Dom.2) | IGDFGLAkAVPEGHEYYR | Activation Loop | -3.9 | 1 | uM |
| JNK-IN-8 | A-375 | NEK9 | LGDYGLAkK | Activation Loop | 12.1 | 1 | uM |
| JNK-IN-8 | A-375 | NEK7 | FFSSkTTAAHSLVGTPYYMSPER | Activation Loop | -1.1 | 1 | uM |
| JNK-IN-8 | A-375 | KS6B1 | LTDFGLCkESIHDGTVTHTFCGTIEYMAPEILMR | Activation Loop | -0.6 | 1 | uM |
| JNK-IN-8 | A-375 | RSK1_domain1 | LTDFGLSkEAIDHEKK | Activation Loop | -15.0 | 1 | uM |
| JNK-IN-8 | A-375 | MET | DMYDkEYYSVHNK | Activation Loop | -16.2 | 1 | uM |
| JNK-IN-8 | A-375 | STLK5 | YSVkVLPWLSPEVLQQNLQGYDAK | Activation Loop | 9.7 | 1 | uM |
| JNK-IN-8 | A-375 | MST3,MST4,YSK1 | LADFGVAGQLTDTQIkR | Activation Loop | 19.4 | 1 | uM |
| JNK-IN-8 | A-375 | JAK1_domain2 | IGDFGLTkAIETDKEYYTVK | Activation Loop | 16.3 | 1 | uM |
| JNK-IN-8 | A-375 | CSK | VSDFGLTkEASSTQDTGK | Activation Loop | 23.4 | 1 | uM |
| JNK-IN-8 | A-375 | NDR1,NDR2 | LSDFGLCTGLkK | Activation Loop | -6.6 | 1 | uM |
| JNK-IN-8 | A-375 | AXL | NCMLNENMSVCVADFGLSkK | Activation Loop | -28.7 | 1 | uM |
| JNK-IN-8 | A-375 | ABL,ARG | LMTGDTYTAHAGAkFPIK | Activation Loop | -6.9 | 1 | uM |
| JNK-IN-8 | A-375 | KS6B2 | LTDFGLCkESIHEGAVTHTFCGTIEYMAPEILVR | Activation Loop | 33.1 | 1 | uM |
| JNK-IN-8 | A-375 | PKR | IGDFGLVTSLKNDGkR | Activation Loop | 1.5 | 1 | uM |
| JNK-IN-8 | A-375 | CSK | VSDFGLTkEASSTQDTGKLPVK | Activation Loop | 4.3 | 1 | uM |
| JNK-IN-8 | A-375 | FYN,SRC,YES | QGAkFPIKWTAPEAALYGR | Activation Loop | 7.9 | 1 | uM |
| JNK-IN-8 | A-375 | FER | QEDGGVYSSSGLkQIPIKWTAPEALNYGR | Activation Loop | -1.4 | 1 | uM |
| JNK-IN-8 | A-375 | EPHA2 | VLEDDPEATYTTSGGkIPIR | Activation Loop | 1.4 | 1 | uM |
| JNK-IN-8 | A-375 | ATR | FYIMMCkPK | ATP | -21.9 | 1 | uM |
| JNK-IN-8 | A-375 | ATM | QLVkGRDDLRQDAVMQQVFQMCNTLLQR | ATP | 10.6 | 1 | uM |
| JNK-IN-8 | A-375 | DNAPK | kGGSWIQEINVAEK | ATP | 12.8 | 1 | uM |