HMS LINCS Project

Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)

• Detail
• Small Molecules Studied
• Cell Lines Studied
• Data Columns
• Results

 Full screen view

Download: Excel (XLSX), Comma-separated (CSV)

Filter results: >>>>

<<<<

Select the entities to show:

Small molecules	Cells
10057:MK2206 10098:Gefitinib 10172:GSK1059615 10232:Dactolisib 10280:Triciribine 10345:Torkinib	50091:AU565 50213:HCC1954 50541:T47D 50583:MCF 10A

Search Clear Form

• |<
• <<
• Previous
• Page 87 of 116
• Next
• >>
• >
• 2151 to 2175 of 2880 records
• per page:25501002501000

Small Molecule	Cell Line	Drug Concentration	Conc Units	Timepoint	Timepoint Units	Measured pERK (Alexa 488)	Measured p-Rb (Alexa 568)	Alexa Fluor 647	Measured p-Akt/p-4EBP1/p-S6 (Alexa 647)	Image
Torkinib	T47D	7.5	nM	6	hr	164.77	78.46	p-4EBP1	425.95
Torkinib	T47D	7.5	nM	24	hr	134.56	75.54	p-4EBP1	293.71
GSK1059615	T47D	31.6	nM	6	hr	175.93	85.52	p-4EBP1	483.66
GSK1059615	T47D	31.6	nM	24	hr	144.33	101.31	p-4EBP1	406.55
MK2206	T47D	31.6	nM	6	hr	99.94	45.83	p-4EBP1	109.15
MK2206	T47D	31.6	nM	24	hr	149.34	93.03	p-4EBP1	348.95
Triciribine	T47D	31.6	nM	6	hr	104.52	59.70	p-4EBP1	189.42
Triciribine	T47D	31.6	nM	24	hr	165.90	102.35	p-4EBP1	358.91
Dactolisib	T47D	31.6	nM	6	hr	78.85	35.77	p-4EBP1	95.11
Dactolisib	T47D	31.6	nM	24	hr	128.11	59.27	p-4EBP1	215.44
Gefitinib	AU565	100.0	nM	6	hr	303.82	65.62	p-4EBP1	88.27
Gefitinib	AU565	100.0	nM	24	hr	484.13	119.44	p-4EBP1	151.09
Torkinib	AU565	31.6	nM	6	hr	399.29	68.77	p-4EBP1	46.60
Torkinib	AU565	31.6	nM	24	hr	393.18	75.82	p-4EBP1	85.28
GSK1059615	AU565	100.0	nM	6	hr	254.26	57.68	p-4EBP1	73.10
GSK1059615	AU565	100.0	nM	24	hr	463.92	116.22	p-4EBP1	184.44
MK2206	AU565	100.0	nM	6	hr	360.15	72.47	p-4EBP1	128.99
MK2206	AU565	100.0	nM	24	hr	347.72	96.13	p-4EBP1	151.95
Triciribine	AU565	100.0	nM	6	hr	270.17	65.85	p-4EBP1	94.28
Triciribine	AU565	100.0	nM	24	hr	517.81	117.75	p-4EBP1	182.57
Dactolisib	AU565	100.0	nM	6	hr	334.11	66.21	p-4EBP1	14.45
Dactolisib	AU565	100.0	nM	24	hr	386.16	67.39	p-4EBP1	25.68
Gefitinib	HCC1954	100.0	nM	6	hr	163.42	52.29	p-4EBP1	65.12
Gefitinib	HCC1954	100.0	nM	24	hr	260.89	125.45	p-4EBP1	145.62
Torkinib	HCC1954	31.6	nM	6	hr	224.65	60.72	p-4EBP1	60.50

• |<
• <<
• Previous
• Page 87 of 116
• Next
• >>
• >
• 2151 to 2175 of 2880 records
• per page:25501002501000

• • HMS LINCS DB home
  • Small molecules
  • Structure search
  • Salt table
  • Cells
  • Cell Lines
  • Primary Cells
  • iPSCs
  • Embryonic Stem Cells
  • Differentiated Cells
  • Proteins
  • Antibodies
  • Other Reagents
  • Unclassified Perturbagens
  • Datasets
  • Libraries
  • Login