HMS LINCS Project

Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)

• Detail
• Small Molecules Studied
• Cell Lines Studied
• Data Columns
• Results

 Full screen view

Download: Excel (XLSX), Comma-separated (CSV)

Filter results: >>>>

<<<<

Select the entities to show:

Small molecules	Cells
10057:MK2206 10098:Gefitinib 10172:GSK1059615 10232:Dactolisib 10280:Triciribine 10345:Torkinib	50091:AU565 50213:HCC1954 50541:T47D 50583:MCF 10A

Search Clear Form

• |<
• <<
• Previous
• Page 88 of 116
• Next
• >>
• >
• 2176 to 2200 of 2880 records
• per page:25501002501000

Small Molecule	Cell Line	Drug Concentration	Conc Units	Timepoint	Timepoint Units	Measured pERK (Alexa 488)	Measured p-Rb (Alexa 568)	Alexa Fluor 647	Measured p-Akt/p-4EBP1/p-S6 (Alexa 647)	Image
Torkinib	HCC1954	31.6	nM	24	hr	254.57	99.93	p-4EBP1	106.33
GSK1059615	HCC1954	100.0	nM	6	hr	466.20	95.44	p-4EBP1	131.04
GSK1059615	HCC1954	100.0	nM	24	hr	279.26	100.61	p-4EBP1	125.77
MK2206	HCC1954	100.0	nM	6	hr	280.37	79.91	p-4EBP1	113.06
MK2206	HCC1954	100.0	nM	24	hr	263.80	118.27	p-4EBP1	145.21
Triciribine	HCC1954	100.0	nM	6	hr	229.88	79.67	p-4EBP1	110.74
Triciribine	HCC1954	100.0	nM	24	hr	270.79	108.49	p-4EBP1	118.87
Dactolisib	HCC1954	100.0	nM	6	hr	216.92	70.29	p-4EBP1	13.19
Dactolisib	HCC1954	100.0	nM	24	hr	253.25	89.81	p-4EBP1	21.84
Gefitinib	MCF 10A	100.0	nM	6	hr	357.47	165.76	p-4EBP1	284.58
Gefitinib	MCF 10A	100.0	nM	24	hr	311.06	173.47	p-4EBP1	183.97
Torkinib	MCF 10A	31.6	nM	6	hr	500.56	171.56	p-4EBP1	212.09
Torkinib	MCF 10A	31.6	nM	24	hr	415.92	185.17	p-4EBP1	126.98
GSK1059615	MCF 10A	100.0	nM	6	hr	324.94	171.47	p-4EBP1	338.34
GSK1059615	MCF 10A	100.0	nM	24	hr	292.65	154.68	p-4EBP1	201.10
MK2206	MCF 10A	100.0	nM	6	hr	364.46	149.83	p-4EBP1	348.28
MK2206	MCF 10A	100.0	nM	24	hr	283.39	167.73	p-4EBP1	192.64
Triciribine	MCF 10A	100.0	nM	6	hr	368.39	151.00	p-4EBP1	350.66
Triciribine	MCF 10A	100.0	nM	24	hr	241.36	162.43	p-4EBP1	182.63
Dactolisib	MCF 10A	100.0	nM	6	hr	343.14	117.01	p-4EBP1	56.72
Dactolisib	MCF 10A	100.0	nM	24	hr	298.00	94.94	p-4EBP1	23.94
Gefitinib	T47D	100.0	nM	6	hr	167.59	90.85	p-4EBP1	463.02
Gefitinib	T47D	100.0	nM	24	hr	143.35	109.50	p-4EBP1	406.42
Torkinib	T47D	31.6	nM	6	hr	159.50	76.22	p-4EBP1	302.14
Torkinib	T47D	31.6	nM	24	hr	125.84	53.32	p-4EBP1	191.58

• |<
• <<
• Previous
• Page 88 of 116
• Next
• >>
• >
• 2176 to 2200 of 2880 records
• per page:25501002501000

• • HMS LINCS DB home
  • Small molecules
  • Structure search
  • Salt table
  • Cells
  • Cell Lines
  • Primary Cells
  • iPSCs
  • Embryonic Stem Cells
  • Differentiated Cells
  • Proteins
  • Antibodies
  • Other Reagents
  • Unclassified Perturbagens
  • Datasets
  • Libraries
  • Login