Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Omipalisib | MDA-MB-157 | -4.4776 | 0.9549 | -6.0816 | -5.4106 | -6.5395 | 0.6444 | 0.2980 | 0.3850 | 6.9857 |
| Omipalisib | MDA-MB-134-VI | -4.4776 | 0.9885 | -7.2176 | -7.2177 | -7.9713 | 0.7442 | 0.0000 | 0.0092 | 4.4619 |
| Omipalisib | Hs 578T | -4.4776 | 0.9865 | -7.1286 | -6.9171 | -7.1638 | 0.7774 | 0.1579 | 0.1652 | 6.6007 |
| Omipalisib | HCC70 | -4.4776 | 0.9751 | -7.5826 | -7.5358 | -8.1178 | 0.8673 | 0.0444 | 0.0464 | 4.2358 |
| Omipalisib | HCC38 | -4.4776 | 0.9805 | -7.1526 | -7.0798 | -7.6187 | 0.9370 | 0.0549 | 0.0595 | 4.8099 |
| Omipalisib | HCC202 | -4.4776 | 0.9925 | -8.0786 | -8.0068 | -8.9423 | 0.9984 | 0.0758 | 0.0760 | 3.7918 |
| Omipalisib | HCC1954 | -4.4776 | 0.9507 | -7.8256 | -7.7807 | -8.1463 | 1.1974 | 0.0450 | 0.0466 | 3.8101 |
| Omipalisib | HCC1937 | -4.4776 | 0.9796 | -7.3266 | -6.9723 | -7.5849 | 0.6869 | 0.2146 | 0.2232 | 5.4591 |
| Omipalisib | HCC1806 | -4.4776 | 0.9844 | -7.2646 | -7.1920 | -7.5727 | 0.6333 | 0.0504 | 0.0665 | 4.7285 |
| Omipalisib | HCC1569 | -4.4776 | 0.9648 | -7.7576 | -7.5276 | -7.7975 | 1.2645 | 0.2412 | 0.2413 | 5.1165 |
| Omipalisib | HCC1428 | -4.4776 | 0.9389 | -7.0436 | -6.6504 | -7.5424 | 0.8643 | 0.2607 | 0.2826 | 5.9711 |
| Omipalisib | HCC1419 | -4.4776 | 0.9393 | -7.8176 | -7.3177 | -8.7550 | 0.7216 | 0.2822 | 0.2850 | 5.2439 |
| Omipalisib | HCC1395 | -4.4776 | 0.9674 | -7.0311 | -6.6125 | -7.3086 | 0.9230 | 0.2903 | 0.2936 | 6.1517 |
| Omipalisib | HCC1143 | -4.4776 | 0.9819 | -7.3286 | -7.1069 | -7.4557 | 0.8936 | 0.1828 | 0.1851 | 5.2906 |
| Omipalisib | CAMA-1 | -4.4776 | 0.9464 | -6.7651 | -6.7125 | -7.1194 | 1.3345 | 0.0749 | 0.0757 | 5.5519 |
| Omipalisib | BT-549 | -4.4776 | 0.9671 | -7.4066 | -7.1032 | -7.3547 | 0.7457 | 0.2033 | 0.2085 | 5.3689 |
| Omipalisib | BT-483 | -4.4776 | 0.9810 | -7.7216 | -7.1924 | -8.8962 | 0.5153 | 0.2330 | 0.2490 | 5.0745 |
| Omipalisib | BT-474 | -4.4776 | 0.9827 | -7.6646 | -7.5992 | -8.3285 | 0.7338 | 0.0520 | 0.0564 | 4.2655 |
| Omipalisib | BT-20 | -4.4776 | 0.9798 | -7.1356 | -7.1020 | -7.8044 | 0.7553 | 0.1163 | 0.1218 | 4.8945 |
| Omipalisib | AU565 | -4.4776 | 0.9675 | -8.1726 | -7.7602 | -8.1358 | 0.7102 | 0.2454 | 0.2472 | 4.7024 |
| Omipalisib | MDA-MB-231 | -4.4776 | 0.8680 | -6.8636 | -6.7312 | -6.7902 | 2.2090 | 0.2450 | 0.2450 | 7.9009 |
| Omipalisib | SK-BR-3 | -4.4776 | 0.9831 | -8.4476 | -8.0186 | -8.4601 | 0.9475 | 0.3040 | 0.3041 | 4.6948 |
| Omipalisib | MCF7 | -4.4776 | 0.9876 | -7.7246 | -7.5630 | -8.1347 | 1.0240 | 0.1581 | 0.1585 | 4.6877 |
| Taxol | ZR75B | -4.4776 | 0.8909 | -7.8031 | -4.4776 | -7.5531 | 1.3873 | 0.6042 | 0.6069 | 6.9605 |
| Taxol | LY2 | -4.4776 | 0.9434 | -7.9566 | -7.7585 | -7.9800 | 3.3255 | 0.3542 | 0.3542 | 5.6728 |