Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| NU6102 | HCC1937 | -4.1759 | 0.9035 | -4.3039 | -4.3039 | -4.2834 | 3.9710 | 0.0000 | 0.2368 | 8.2712 |
| NU6102 | HCC1954 | -4.1759 | 0.7615 | -4.2292 | -4.2292 | -4.3284 | 1.8850 | 0.0000 | 0.4424 | 8.2964 |
| NU6102 | HCC202 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| NU6102 | HCC38 | -4.1759 | 0.8599 | -4.9315 | -4.9316 | -5.0834 | 1.3550 | 0.0000 | 0.0864 | 6.8630 |
| NU6102 | HCC70 | -4.1759 | 0.9196 | -4.6708 | -4.6708 | -4.7391 | 3.4915 | 0.0000 | 0.0200 | 7.4141 |
| NU6102 | Hs 578T | -4.1759 | 0.9365 | -4.5872 | -4.5664 | -4.6685 | 1.7100 | 0.0393 | 0.1981 | 7.9296 |
| NU6102 | MB 157 | -4.1759 | 0.9438 | -4.8498 | -4.7875 | -4.8482 | 3.9970 | 0.2180 | 0.2196 | 8.0111 |
| NU6102 | MDA-MB-134-VI | -4.1759 | 0.9436 | -4.5301 | -4.4669 | -4.6218 | 3.9970 | 0.2205 | 0.2493 | 8.4107 |
| NU6102 | MDA-MB-157 | -4.1759 | 0.7402 | -4.2713 | -4.2713 | -4.2761 | 3.9920 | 0.0000 | 0.2938 | 8.3532 |
| NU6102 | MDA-MB-175-VII | -4.1759 | 0.7711 | -4.1256 | -4.1759 | -4.2892 | 3.9930 | 0.0000 | 0.6138 | 8.3900 |
| NU6102 | MDA-MB-361 | -4.1759 | 0.8448 | -4.3712 | -4.3628 | -4.4830 | 3.9995 | 0.1068 | 0.4135 | 8.4518 |
| NU6102 | MDA-MB-436 | -4.1759 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 9.3015 |
| NU6102 | MDA-MB-453 | -4.1759 | 0.8966 | -4.6778 | -4.6778 | -4.9268 | 1.7790 | 0.0000 | 0.1134 | 7.4206 |
| NU6102 | MDA-MB-468 | -4.1759 | 0.8918 | -4.7650 | -4.7649 | -4.8581 | 2.1890 | 0.0000 | 0.0488 | 7.8701 |
| NU6102 | T47D | -4.1759 | 0.9109 | -4.3671 | -4.3671 | -4.5208 | 1.2140 | 0.0000 | 0.3694 | 7.9377 |
| NU6102 | UACC-812 | -4.1759 | 0.8145 | -4.5294 | -4.5294 | -4.5361 | 4.0000 | 0.0000 | 0.0371 | 7.6594 |
| NU6102 | UACC-893 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| NU6102 | ZR-75-1 | -4.1759 | 0.7503 | -4.5230 | -4.5230 | -5.0209 | 1.0150 | 0.0000 | 0.3266 | 7.3270 |
| NU6102 | 184B5 | -4.1759 | 0.9695 | -5.2019 | -5.2023 | -5.4148 | 1.3670 | 0.0000 | 0.0380 | 7.0339 |
| NU6102 | HCC1187 | -4.1759 | 0.9731 | -4.8154 | -4.8155 | -5.1280 | 1.2560 | 0.0000 | 0.1359 | 7.4699 |
| NU6102 | MCF 10A | -4.1759 | 0.9584 | -5.2469 | -5.2472 | -5.3280 | 1.0140 | 0.0000 | 0.0758 | 7.0416 |
| NU6102 | MCF 10F | -4.1759 | 0.9567 | -4.7831 | -4.7832 | -4.9822 | 2.0600 | 0.0000 | 0.0531 | 7.7437 |
| NU6102 | SUM1315MO2 | -4.1759 | 0.9502 | -4.8489 | -4.8489 | -5.4507 | 1.1639 | 0.0000 | 0.1457 | 7.4386 |
| NU6102 | SUM149PT | -4.1759 | 0.9256 | -5.0238 | -5.0239 | -5.1341 | 1.0803 | 0.0000 | 0.1206 | 6.9129 |
| NU6102 | SUM159PT | -4.1759 | 0.9437 | -4.9393 | -4.9393 | -4.9695 | 1.8280 | 0.0000 | 0.0387 | 6.9762 |