Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Carboplatin | T47DKBLUC | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Carboplatin | 600MPE | -2.8697 | 0.9703 | -3.5866 | -3.5347 | -3.8715 | 1.8735 | 0.1009 | 0.1791 | 7.6810 |
| Carboplatin | HCC2185 | -2.8697 | 0.9689 | -3.9498 | -3.9499 | -4.7448 | 1.1400 | 0.0000 | 0.0584 | 7.0423 |
| Carboplatin | HCC3153 | -2.8697 | 0.9647 | -4.3037 | -4.2518 | -4.3946 | 3.2145 | 0.1552 | 0.1553 | 6.7407 |
| Carboplatin | LY2 | -2.8697 | 0.9545 | -4.0292 | -4.0061 | -4.3549 | 1.1618 | 0.0333 | 0.0815 | 6.8407 |
| Carboplatin | ZR75B | -2.8697 | 0.8751 | -3.1619 | -3.1618 | -3.3597 | 1.8530 | 0.0000 | 0.2233 | 8.4172 |
| CGC-11047 | MCF7 | -2.3010 | 0.9410 | -2.4693 | -2.4693 | -3.2887 | 0.4982 | 0.0000 | 0.2197 | 6.9620 |
| CGC-11047 | SK-BR-3 | -2.3010 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 7.6541 |
| CGC-11047 | MDA-MB-231 | -2.3010 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 5.6882 |
| CGC-11047 | AU565 | -2.3010 | 0.8319 | -3.4700 | -3.4698 | -3.6213 | 2.4360 | 0.0000 | 0.0014 | 6.2984 |
| CGC-11047 | BT-20 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| CGC-11047 | BT-474 | -2.3010 | 0.8723 | -3.2125 | -3.2125 | -3.9275 | 0.6843 | 0.0000 | 0.1458 | 6.6174 |
| CGC-11047 | BT-483 | -2.3010 | 0.8210 | -2.7831 | -2.4601 | -3.2758 | 1.5504 | 0.2775 | 0.4450 | 8.1875 |
| CGC-11047 | BT-549 | -2.3010 | 0.8254 | -4.3850 | -4.3848 | NaN | 0.3120 | 0.0000 | 0.1835 | 5.2583 |
| CGC-11047 | CAMA-1 | -2.3010 | 0.9190 | -2.7147 | -2.7148 | -2.8581 | 2.9430 | 0.0000 | 0.0571 | 7.0804 |
| CGC-11047 | HCC1143 | -2.3010 | 0.8885 | -3.5140 | -3.5138 | -4.3686 | 0.8045 | 0.0000 | 0.0956 | 6.5950 |
| CGC-11047 | HCC1395 | -2.3010 | 0.7018 | -3.4850 | -3.4848 | -4.2788 | 1.0160 | 0.0000 | 0.0590 | 6.2864 |
| CGC-11047 | HCC1419 | -2.3010 | 0.8675 | -3.3720 | -3.3718 | -4.8529 | 0.5490 | 0.0000 | 0.2061 | 6.4600 |
| CGC-11047 | HCC1428 | -2.3010 | 0.8375 | -3.1710 | -3.1710 | -4.2068 | 0.8161 | 0.0000 | 0.1829 | 6.7133 |
| CGC-11047 | HCC1569 | -2.3010 | 0.8386 | -2.8474 | -2.8474 | -3.5307 | 0.4205 | 0.0000 | 0.3431 | 7.1806 |
| CGC-11047 | HCC1806 | -2.3010 | 0.8290 | -4.1880 | -4.1877 | -4.6384 | 0.4628 | 0.0000 | 0.1181 | 5.7011 |
| CGC-11047 | HCC1937 | -2.3010 | 0.8954 | -4.0020 | -4.0022 | NaN | 0.3294 | 0.0000 | 0.2236 | 5.7607 |
| CGC-11047 | HCC1954 | -2.3010 | 0.9366 | -5.6110 | -5.5342 | -6.5631 | 0.4859 | 0.0000 | 0.0262 | 3.9887 |
| CGC-11047 | HCC202 | -2.3010 | 0.8206 | -3.2353 | -3.2354 | -5.2705 | 0.9265 | 0.0000 | 0.1452 | 6.5999 |
| CGC-11047 | HCC38 | -2.3010 | 0.8844 | -4.1210 | -4.1212 | -4.4522 | 0.4957 | 0.0000 | 0.1148 | 5.7082 |