Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Valproic acid | HCC202 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Valproic acid | HCC38 | -1.8239 | 0.9533 | -2.9274 | -2.9272 | -3.0952 | 1.5090 | 0.0000 | 0.0251 | 6.6679 |
| Valproic acid | HCC70 | -1.8239 | 0.9572 | -2.8042 | -2.8042 | -3.0349 | 1.6965 | 0.0000 | 0.0241 | 6.9108 |
| Valproic acid | Hs 578T | -1.8239 | 0.9235 | -2.1785 | -2.1785 | -2.2506 | 1.1950 | 0.0000 | 0.2738 | 7.6335 |
| Valproic acid | MB 157 | -1.8239 | 0.8521 | -2.2654 | -2.1761 | -2.3415 | 1.2690 | 0.1149 | 0.3059 | 8.1743 |
| Valproic acid | MDA-MB-134-VI | -1.8239 | 0.9616 | -2.6459 | -2.6459 | -3.1453 | 1.2720 | 0.0000 | 0.0830 | 7.1326 |
| Valproic acid | MDA-MB-157 | -1.8239 | 0.8963 | -2.4830 | -2.3798 | -2.6696 | 1.4880 | 0.1487 | 0.2293 | 8.0577 |
| Valproic acid | MDA-MB-175-VII | -1.8239 | 0.8935 | -2.3661 | -2.3662 | -3.1952 | 0.8511 | 0.0000 | 0.2377 | 7.1843 |
| Valproic acid | MDA-MB-361 | -1.8239 | 0.9727 | -2.4008 | -2.4008 | -2.8889 | 2.4440 | 0.0000 | 0.0406 | 7.5667 |
| Valproic acid | MDA-MB-436 | -1.8239 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.6146 |
| Valproic acid | MDA-MB-453 | -1.8239 | 0.9602 | -2.8879 | -2.8875 | -3.1850 | 1.3750 | 0.0000 | 0.0333 | 6.8045 |
| Valproic acid | MDA-MB-468 | -1.8239 | 0.9087 | -2.3315 | -2.3146 | -2.3679 | 3.9990 | 0.0718 | 0.0804 | 7.6845 |
| Valproic acid | T47D | -1.8239 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 7.1259 |
| Valproic acid | UACC-812 | -1.8239 | 0.8910 | -2.0618 | -2.0618 | -2.6202 | 0.8397 | 0.0000 | 0.3870 | 7.7370 |
| Valproic acid | UACC-893 | -1.8239 | 0.9394 | -2.2438 | -2.2438 | -2.9200 | 1.5300 | 0.0000 | 0.1856 | 7.5722 |
| Valproic acid | ZR-75-1 | -1.8239 | 0.9501 | -2.2991 | -2.2991 | -2.5867 | 1.6350 | 0.0000 | 0.1432 | 7.1279 |
| Valproic acid | 184B5 | -1.8239 | 0.8933 | -2.6722 | -2.5296 | -3.0885 | 0.5531 | 0.0831 | 0.3154 | 7.1777 |
| Valproic acid | HCC1187 | -1.8239 | 0.9690 | -2.5786 | -2.5786 | -2.8262 | 1.3240 | 0.0000 | 0.0910 | 7.1492 |
| Valproic acid | MCF 10A | -1.8239 | 0.9654 | -2.9349 | -2.9352 | -3.0146 | 1.4670 | 0.0000 | 0.0229 | 7.0702 |
| Valproic acid | MCF 10F | -1.8239 | 0.9500 | -2.3554 | -2.3554 | -2.3415 | 3.4430 | 0.0000 | 0.0146 | 7.6306 |
| Valproic acid | SUM1315MO2 | -1.8239 | 0.9517 | -2.4710 | -2.4249 | -2.6560 | 3.0330 | 0.1360 | 0.1571 | 7.9566 |
| Valproic acid | SUM149PT | -1.8239 | 0.9370 | -2.7799 | -2.7801 | -2.9160 | 1.2545 | 0.0000 | 0.0610 | 6.8020 |
| Valproic acid | SUM159PT | -1.8239 | 0.9496 | -2.9449 | -2.9446 | -2.9592 | 1.1440 | 0.0000 | 0.0496 | 6.6356 |
| Valproic acid | SUM185PE | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Valproic acid | SUM225CWN | -1.8239 | 0.8920 | -2.4391 | -2.4391 | -2.7630 | 2.0665 | 0.0000 | 0.0543 | 7.6744 |