XMD-12 KiNativ -- single dose experiment - Dataset (ID:20103)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| XMD-12 | HeLa | KSR1,KSR2 | SkNVFYDNGK | Protein Kinase Domain | -2.4 | 10 | uM |
| XMD-12 | HeLa | LATS2 | VDTHALYAMkTLR | Lys1 | -22.6 | 10 | uM |
| XMD-12 | HeLa | LYN | VAVkTLKPGTMSVQAFLEEANLMK | Lys1 | 51.7 | 10 | uM |
| XMD-12 | PC-3 | M3K2 | VYLCYDVDTGRELAVkQVQFDPDSPETSKEVNALECEIQLLK | Lys1 | 66.5 | 10 | uM |
| XMD-12 | HeLa | MAP3K5 | DIkGDNVLINTYSGVLK | Lys2 | 1.8 | 10 | uM |
| XMD-12 | HeLa | MAPKAPK3 | KYAVTDDYQLSkQVLGLGVNGK | ATP Loop | -6.2 | 10 | uM |
| XMD-12 | PC-3 | MARK2 | EVAVkIIDKTQLNSSSLQK | Lys1 | 45.8 | 10 | uM |
| XMD-12 | PC-3 | MARK3,MARK4 | EVAIkIIDK | Lys1 | 64.2 | 10 | uM |
| XMD-12 | HeLa | MASTL | LYAVkVVK | Lys1 | 7.0 | 10 | uM |
| XMD-12 | PC-3 | MET | DMYDkEYYSVHNK | Activation Loop | -12.6 | 10 | uM |
| XMD-12 | PC-3 | MRCKb | NHHVHLYPWSSLDGAEGSFDIkLPETK | Other | 2.8 | 10 | uM |
| XMD-12 | HeLa | p38a | DLkPSNLAVNEDCELK | Lys2 | -20.4 | 10 | uM |
| XMD-12 | PC-3 | p38a | DLkPSNLAVNEDCELK | Lys2 | -1.5 | 10 | uM |
| XMD-12 | HeLa | MK14 | QELNkTIWEVPER | Other | -2.7 | 10 | uM |
| XMD-12 | PC-3 | MK14 | QELNkTIWEVPER | Other | -5.0 | 10 | uM |
| XMD-12 | HeLa | PAN3 | VMDPTkILITGK | -13.7 | 10 | uM | |
| XMD-12 | HeLa | PEK | DLkPSNIFFTMDDVVK | Lys2 | -25.8 | 10 | uM |
| XMD-12 | PC-3 | PEK | DLkPSNIFFTMDDVVK | Lys2 | 20.0 | 10 | uM |
| XMD-12 | HeLa | PIK3CG | KkPLWLEFK | ATP | 5.4 | 10 | uM |
| XMD-12 | HeLa | PKN1 | GHFGkVLLSEFRPSGELFAIK | Lys1 | -20.6 | 10 | uM |
| XMD-12 | HeLa | PLK1 | DLkLGNLFLNEDLEVK | Lys2 | 10.9 | 10 | uM |
| XMD-12 | PC-3 | ROCK1 | kLQLELNQER | Other | -25.8 | 10 | uM |
| XMD-12 | PC-3 | RON | IQCAIkSLSR | Lys1 | 15.8 | 10 | uM |
| XMD-12 | PC-3 | SRPK1 | IIHTDIkPENILLSVNEQYIR | Lys2 | 22.2 | 10 | uM |
| XMD-12 | PC-3 | SRPK1/2 | FVAMkVVK | Lys1 | 44.7 | 10 | uM |