XMD-12 KiNativ -- single dose experiment - Dataset (ID:20103)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
XMD-12 HeLa ULK3
EVVAIkCVAK
Lys1
34.2
 10
uM
XMD-12 PC-3 EGFR
LLGAEEKEYHAEGGkVPIK
Activation Loop
-26.4
 10
uM
XMD-12 HeLa KPCI
IYAMkVVK
Lys1
-50.8
 10
uM
XMD-12 PC-3 PRP4
CNILHADIkPDNILVNESK
Lys2
-13.9
 10
uM
XMD-12 PC-3 ANPb
GMAFLHNSIISSHGSLkSSNCVVDSR
Lys2
-7.0
 10
uM
XMD-12 PC-3 CaMK2a,CaMK2b,CaMK2d,CaMK2g
DLkPENLLLASK
Lys2
23.5
 10
uM
XMD-12 PC-3 CDK5
ETHEIVALkR
Lys1
4.5
 10
uM
XMD-12 PC-3 CK2a2
DVkPHNVMIDHQQK
Lys2
33.4
 10
uM
XMD-12 PC-3 EGFR
ITDFGLAkLLGAEEK
Activation Loop
-24.0
 10
uM
XMD-12 PC-3 EphA1
LLDDFDGTYETQGGkIPIR
Activation Loop
46.7
 10
uM
XMD-12 PC-3 EPHA2
EVPVAIkTLK
Lys1
8.4
 10
uM
XMD-12 PC-3 EphA7
VIEDDPEAVYTTTGGkIPVR
Activation Loop
-21.4
 10
uM
XMD-12 PC-3 EPHB2
FLEDDTSDPTYTSALGGkIPIR
Activation Loop
27.3
 10
uM
XMD-12 HeLa GCN2
LDGCCYAVkR
Lys1
-5.1
 10
uM
XMD-12 PC-3 GCN2
LDGCCYAVkR
Lys1
-12.4
 10
uM
XMD-12 HeLa JAK2 domain2
IGDFGLTkVLPQDKEYYK
Activation Loop
-7.6
 10
uM
XMD-12 HeLa JAK3 domain2
IADFGLAkLLPLDKDYYVVR
Activation Loop
12.8
 10
uM
XMD-12 PC-3 M4K3
NVNTGELAAIkVIK
Lys1
61.9
 10
uM
XMD-12 PC-3 MET
DMYDKEYYSVHNkTGAK
Activation Loop
50.3
 10
uM
XMD-12 PC-3 MRCKb
DIkPDNVLLDVNGHIR
Lys2
-32.7
 10
uM
XMD-12 PC-3 MK11
QELNkTVWEVPQR
Other
31.8
 10
uM
XMD-12 PC-3 PDK1
EYAIkILEK
Lys1
-7.3
 10
uM
XMD-12 PC-3 PI42C
ELPTLkDMDFLNK
ATP
58.6
 10
uM
XMD-12 HeLa PKD2
DVAVkVIDK
Lys1
5.0
 10
uM
XMD-12 PC-3 PKD2
DVAVkVIDK
Lys1
33.2
 10
uM