XMD-12 KiNativ -- single dose experiment - Dataset (ID:20103)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
XMD-12 HeLa RIPK3
DLkPSNVLLDPELHVK
Lys2
1.9
 10
uM
XMD-12 HeLa RSK1 domain1
LTDFGLSkEAIDHEK
Activation Loop
27.4
 10
uM
XMD-12 HeLa RSK1,RSK4 domain1
VLGQGSFGkVFLVR
ATP Loop
-11.2
 10
uM
XMD-12 PC-3 SLK
ETSVLAAAkVIDTK
Lys1
34.1
 10
uM
XMD-12 HeLa SYK
ISDFGLSkALR
Activation Loop
2.1
 10
uM
XMD-12 HeLa TLK1
YAAVkIHQLNK
Lys1
-23.8
 10
uM
XMD-12 PC-3 TLK1
YAAVkIHQLNK
Lys1
-47.5
 10
uM
XMD-12 HeLa ULK1
DLkPQNILLSNPAGR
Lys2
-9.3
 10
uM
XMD-12 HeLa AurB
SHFIVALkVLFK
Lys1
95.0
 10
uM
XMD-12 PC-3 CLK2
LTHTDLkPENILFVNSDYELTYNLEK
Lys2
5.8
 10
uM
XMD-12 HeLa IRAK3
SHLEHQSCTINMTSSSSkHLWYMPEEYIR
Protein Kinase Domain
23.7
 10
uM
XMD-12 HeLa MYO3A,MYO3B
DVkGNNILLTTEGGVK
Lys2
-1.3
 10
uM
XMD-12 PC-3 SNRK
DLkPENVVFFEK
Lys2
-15.0
 10
uM
XMD-12 HeLa TEC
YVLDDQYTSSSGAkFPVK
Activation Loop
11.2
 10
uM
XMD-12 HeLa ILK
WQGIVVkVLK
Lys1
-4.0
 10
uM
XMD-12 PC-3 ILK
WQGIVVkVLK
Lys1
-12.5
 10
uM