XMD-12 KiNativ -- single dose experiment - Dataset (ID:20103)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
XMD-12 PC-3 TAOK2
DVkAGNILLSEPGLVK
Lys2
91.3
10
uM
XMD-12 HeLa TBK1
TGDLFAIkVFNNISFLRPVDVQMR
Lys1
10
uM
XMD-12 HeLa TLK1
YLNEIKPPIIHYDLkPGNILLVDGTACGEIK
Lys2
-20.1
10
uM
XMD-12 PC-3 TLK1
YLNEIKPPIIHYDLkPGNILLVDGTACGEIK
Lys2
-7.5
10
uM
XMD-12 PC-3 TLK2
YVAVkIHQLNK
Lys1
-11.7
10
uM
XMD-12 HeLa WEE1
YIHSMSLVHMDIkPSNIFISR
Lys2
10
uM
XMD-12 HeLa Wnk1,Wnk2,Wnk3
DLkCDNIFITGPTGSVK
Lys2
2.8
10
uM
XMD-12 PC-3 Wnk1,Wnk2,Wnk4
IGDLGLATLkR
Activation Loop
-11.9
10
uM
XMD-12 PC-3 WNK4
DLkCDNVFITGPTGSVK
Lys2
-10.1
10
uM
XMD-12 HeLa MLTK
WISQDKEVAVKk
Lys1
11.4
10
uM
XMD-12 PC-3 MLTK
WISQDKEVAVKk
Lys1
15.8
10
uM
XMD-12 HeLa ZC1/HGK,ZC2/TNIK,ZC3/MINK
DIkGQNVLLTENAEVK
Lys2
22.4
10
uM
XMD-12 PC-3 ZC1/HGK,ZC2/TNIK,ZC3/MINK
DIkGQNVLLTENAEVK
Lys2
-7.1
10
uM
XMD-12 HeLa BARK1
DLkPANILLDEHGHVR
Lys2
-4.3
10
uM
XMD-12 HeLa BTK
GQYDVAIkMIK
Lys1
28.3
10
uM
XMD-12 HeLa CAMK1D
LFAVkCIPK
Lys1
-29.5
10
uM
XMD-12 PC-3 CDK5
DLkPQNLLINR
Lys2
12.5
10
uM
XMD-12 HeLa CHK1
DIkPENLLLDER
Lys2
14.9
10
uM
XMD-12 HeLa CHK2
DLkPENVLLSSQEEDCLIK
Lys2
17.6
10
uM
XMD-12 PC-3 CHK2
DLkPENVLLSSQEEDCLIK
Lys2
29.7
10
uM
XMD-12 HeLa DGKA
IDPVPNTHPLLVFVNPkSGGK
ATP
5.9
10
uM
XMD-12 PC-3 EPHB4
FLEENSSDPTYTSSLGGkIPIR
Activation Loop
51.7
10
uM
XMD-12 HeLa FES
LRADNTLVAVkSCR
Lys1
-2.5
10
uM
XMD-12 HeLa HPK1
DKVSGDLVALkMVK
Lys1
69.0
10
uM
XMD-12 HeLa IKKE
SGELVAVkVFNTTSYLRPR
Lys1
14.6
10
uM