JWE-035 KiNativ -- single dose experiment - Dataset (ID:20100)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| JWE-035 | HeLa | ZC1/HGK,ZC2/TNIK,ZC3/MINK | DIkGQNVLLTENAEVK | Lys2 | 3.8 | 10 | uM |
| JWE-035 | PC-3 | ZC1/HGK,ZC2/TNIK,ZC3/MINK | DIkGQNVLLTENAEVK | Lys2 | 3.1 | 10 | uM |
| JWE-035 | PC-3 | WNK4 | DLkCDNVFITGPTGSVK | Lys2 | -13.1 | 10 | uM |
| JWE-035 | PC-3 | Wnk1,Wnk2,Wnk4 | IGDLGLATLkR | Activation Loop | -0.3 | 10 | uM |
| JWE-035 | HeLa | Wnk1,Wnk2,Wnk3 | DLkCDNIFITGPTGSVK | Lys2 | 10.7 | 10 | uM |
| JWE-035 | HeLa | WEE1 | YIHSMSLVHMDIkPSNIFISR | Lys2 | 14.5 | 10 | uM |
| JWE-035 | HeLa | ULK3 | EVVAIkCVAK | Lys1 | 8.2 | 10 | uM |
| JWE-035 | HeLa | ULK1 | DLkPQNILLSNPAGR | Lys2 | 22.8 | 10 | uM |
| JWE-035 | PC-3 | TLK2 | YVAVkIHQLNK | Lys1 | 12.7 | 10 | uM |
| JWE-035 | PC-3 | TLK1 | YAAVkIHQLNK | Lys1 | 37.8 | 10 | uM |
| JWE-035 | PC-3 | TLK1 | YLNEIKPPIIHYDLkPGNILLVDGTACGEIK | Lys2 | -1.1 | 10 | uM |
| JWE-035 | HeLa | TLK1 | YAAVkIHQLNK | Lys1 | -48.4 | 10 | uM |
| JWE-035 | HeLa | TLK1 | YLNEIKPPIIHYDLkPGNILLVDGTACGEIK | Lys2 | -10.4 | 10 | uM |
| JWE-035 | HeLa | TEC | YVLDDQYTSSSGAkFPVK | Activation Loop | 12.1 | 10 | uM |
| JWE-035 | HeLa | TBK1 | TGDLFAIkVFNNISFLRPVDVQMR | Lys1 | 28.7 | 10 | uM |
| JWE-035 | PC-3 | TAOK2 | DVkAGNILLSEPGLVK | Lys2 | 71.7 | 10 | uM |
| JWE-035 | HeLa | TAO1,TAOK3 | DIkAGNILLTEPGQVK | Lys2 | -2.0 | 10 | uM |
| JWE-035 | PC-3 | TAO1,TAOK3 | DIkAGNILLTEPGQVK | Lys2 | 31.5 | 10 | uM |
| JWE-035 | HeLa | SYK | ISDFGLSkALR | Activation Loop | -0.1 | 10 | uM |
| JWE-035 | HeLa | STLK5 | YSVkVLPWLSPEVLQQNLQGYDAK | Activation Loop | 75.6 | 10 | uM |
| JWE-035 | PC-3 | SRPK1/2 | FVAMkVVK | Lys1 | -6.3 | 10 | uM |
| JWE-035 | PC-3 | SRPK1 | IIHTDIkPENILLSVNEQYIR | Lys2 | 9.8 | 10 | uM |
| JWE-035 | PC-3 | SRC | VAIkTLKPGTMSPEAFLQEAQVMK | Lys1 | -2.0 | 10 | uM |
| JWE-035 | PC-3 | SNRK | DLkPENVVFFEK | Lys2 | 5.9 | 10 | uM |
| JWE-035 | HeLa | SMG1 | DTVTIHSVGGTITILPTkTKPK | ATP | -0.6 | 10 | uM |