JWE-035 KiNativ -- single dose experiment - Dataset (ID:20100)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
JWE-035 HeLa ABL,ARG
LMTGDTYTAHAGAkFPIK
Activation Loop
91.1
10
uM
JWE-035 HeLa ACK
TVSVAVkCLKPDVLSQPEAMDDFIR
Lys1
30.9
10
uM
JWE-035 PC-3 AGK
ATVFLNPAACkGK
ATP
-18.2
10
uM
JWE-035 HeLa AMPKa1,AMPKa2
DLkPENVLLDAHMNAK
Lys2
63.0
10
uM
JWE-035 PC-3 AMPKa1,AMPKa2
DLkPENVLLDAHMNAK
Lys2
57.2
10
uM
JWE-035 HeLa AMPKa1,AMPKa2
VAVkILNR
Lys1
55.4
10
uM
JWE-035 PC-3 AMPKa1,AMPKa2
VAVkILNR
Lys1
75.7
10
uM
JWE-035 HeLa ARAF
DLkSNNIFLHEGLTVK
Lys2
6.2
10
uM
JWE-035 HeLa ATR
FYIMMCkPK
ATP
8.1
10
uM
JWE-035 PC-3 ATR
FYIMMCkPK
ATP
3.6
10
uM
JWE-035 HeLa BRAF
DLkSNNIFLHEDLTVK
Lys2
4.5
10
uM
JWE-035 HeLa CaMK1a
LVAIkCIAK
Lys1
0.8
10
uM
JWE-035 HeLa CaMK2g
TSTQEYAAkIINTK
Lys1
19.9
10
uM
JWE-035 PC-3 CaMK2g
TSTQEYAAkIINTK
Lys1
21.0
10
uM
JWE-035 PC-3 CASK
ETGQQFAVkIVDVAK
Lys1
16.0
10
uM
JWE-035 PC-3 CDK10
DLkVSNLLMTDK
Lys2
12.9
10
uM
JWE-035 PC-3 CDK11,CDK8
DLkPANILVMGEGPER
Lys2
0.7
10
uM
JWE-035 HeLa CDK2
DLkPQNLLINTEGAIK
Lys2
6.7
10
uM
JWE-035 PC-3 CDK2
DLkPQNLLINTEGAIK
Lys2
14.8
10
uM
JWE-035 PC-3 CDK5
NRETHEIVALkR
Lys1
34.0
10
uM
JWE-035 HeLa CDK7
DLkPNNLLLDENGVLK
Lys2
54.2
10
uM
JWE-035 PC-3 CDK9
DMkAANVLITR
Lys2
4.2
10
uM
JWE-035 PC-3 CHK2
VAIkIISK
Lys1
42.7
10
uM
JWE-035 PC-3 KC1A
DIkPDNFLMGIGR
Lys2
-0.4
10
uM
JWE-035 PC-3 CK1d,CK1e
DVkPDNFLMGLGKK
Lys2
-1.7
10
uM
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